Tag

Renal Function

18 genetic variants with this tag.

RSID	Gene	Description	Category
rs10177833	SLC4A5	Intronic variant in the sodium bicarbonate cotransporter gene strongly associ...	Blood Pressure & Hypertension	Renal Function	Strong
rs1165196	SLC17A1 SLC17A1 T269I (NPT1)	Missense variant in SLC17A1 (NPT1) encoding a Thr269Ile substitution; the G a...	Uric Acid & Kidney Function	Renal Function	Moderate
rs1165205	SLC17A3 SLC17A3 variant (NPT4)	Intronic variant in SLC17A3, encoding the renal apical urate efflux transport...	Uric Acid & Kidney Function	Renal Function	Moderate
rs11950646	SLC23A1	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Renal Function	Moderate
rs1183201	SLC17A1	Intronic variant in SLC17A1 (NPT1), the renal apical urate efflux transporter...	Uric Acid & Kidney Function	Renal Function	Strong
rs12510549	SLC2A9	Intergenic variant in the SLC2A9 urate-transporter locus — the C allele is as...	Uric Acid & Kidney Function	Renal Function	Strong
rs147647315	SLC22A12 URAT1 R90H	Missense variant in URAT1 reducing urate reabsorption in the kidney, causing ...	Uric Acid & Kidney Function	Renal Function	Strong
rs12704795	PON2 PON2 intron 1 variant	Intronic PON2 haplotype tag; the A allele is associated with reduced intracel...	Vascular Inflammation & Remodeling	Renal Function	Moderate
rs35929607	STK39	Intronic variant in the SPAK kinase gene that has been studied for associatio...	Blood Pressure & Hypertension	Renal Function	Emerging
rs146582474	SLC7A7	Finnish founder splice acceptor mutation abolishing y+LAT1 transport activity...	Metabolic Enzymes & Rare Disorders	Renal Function	Established
rs3755351	ADD2	Intronic variant in beta-adducin modulating renal Na+/K+-ATPase trafficking a...	Blood Pressure & Hypertension	Renal Function	Emerging
rs3825016	SLC22A12	Synonymous coding variant in the URAT1 renal urate transporter; the C allele ...	Uric Acid & Kidney Function	Renal Function	Moderate
rs3865418	NEDD4L	Intronic NEDD4L variant that tags reduced ubiquitin-ligase activity toward th...	Blood Pressure & Hypertension	Renal Function	Moderate
rs7305099	WNK1 WNK1 intronic variant	Intronic WNK1 variant where the G allele is associated with increased essenti...	Blood Pressure & Hypertension	Renal Function	Moderate
rs73885316	APOL1 p.N264K	Protective missense modifier in APOL1 that abolishes G2 risk allele cytotoxic...	Uric Acid & Kidney Function	Renal Function	Strong
rs193922485	HNF1B	Rare HNF1B splice-region intronic variant of uncertain significance, found ne...	Blood Sugar & Diabetes	Renal Function	Emerging
rs73885319	APOL1 G1 S342G	APOL1 G1 kidney disease risk variant — missense change that evolved for trypa...	Cholesterol & Lipoproteins	Renal Function	Established
rs6596471	SLC23A1 SLC23A1 variant	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Renal Function	Moderate