Tag
Skin
14 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10794648 | IFNLR1/GRHL3 | Intergenic regulatory variant near IFNLR1 that contacts GRHL3 via chromatin l... | Interferon Signaling & Systemic Autoimmune | Moderate | |
| rs11652075 | CARD14 CARD14 Arg820Trp (R820W) | Missense variant in the keratinocyte NF-κB scaffold protein CARD14 that modes... | Psoriasis & Spondyloarthropathy | Strong | |
| rs12191877 | HLA-C Tag for *06:02 | Tag SNP for HLA-C*06:02, the strongest genetic risk factor for psoriasis, det... | Psoriasis & Spondyloarthropathy | Established | |
| rs17728338 | TNIP1 TNIP1/ABIN1 variant | Intergenic regulatory variant near TNIP1 whose A allele reduces ABIN1-mediate... | Psoriasis & Spondyloarthropathy | Strong | |
| rs12123821 | FLG Filaggrin skin barrier variant | Common regulatory variant in the FLG locus associated with impaired skin barr... | Allergy & Atopic Disease | Strong | |
| rs2256774 | IL2RA | Intronic IL2RA variant independently associated with psoriasis susceptibility | Autoimmune Tolerance & T-Cell Regulation | Moderate | |
| rs3212227 | IL12B 3'UTR | IL12B 3'-UTR variant forming the canonical two-SNP psoriasis risk haplotype w... | Psoriasis & Spondyloarthropathy | Strong | |
| rs3213094 | IL12B Promoter-region | Intronic IL12B variant in linkage with the promoter-regulatory haplotype; T a... | Psoriasis & Spondyloarthropathy | Moderate | |
| rs3805435 | TNIP1 | Intronic variant in the GPX3/TNIP1 regulatory locus on chromosome 5; the C al... | Psoriasis & Spondyloarthropathy | Moderate | |
| rs1420101 | IL1RL1 | Intronic regulatory variant in IL1RL1 that lowers soluble ST2 (sST2) decoy re... | Allergy & Atopic Disease | Strong | |
| rs610604 | TNFAIP3 | Intronic variant in TNFAIP3 whose G allele is the primary psoriasis susceptib... | Psoriasis & Spondyloarthropathy | Strong | |
| rs61751629 | CARD14 Glu422Lys | Rare missense variant in the keratinocyte NF-κB scaffold protein CARD14 that ... | Psoriasis & Spondyloarthropathy | Emerging | |
| rs7125552 | EMSY EMSY Haplotype Partner Allergy Variant | Intronic EMSY variant that defines the high-risk haplotype at 11q13.5; the G ... | Allergy & Atopic Disease | Moderate | |
| rs7927894 | EMSY | Regulatory variant near the EMSY/C11orf30 locus; T allele is the broadest kno... | Allergy & Atopic Disease | Strong |