Tag

Base Excision Repair

5 genetic variants with this tag.

RSID	Gene	Description	Category
rs1799782	XRCC1 R194W	Missense variant in the linker region of XRCC1 that disrupts interaction with...	Cancer Risk	Base Excision Repair	Strong
rs25487	XRCC1 R399Q	Base excision repair scaffold protein that coordinates repair of oxidative DN...	Cancer Risk	Base Excision Repair	Strong
rs34612342	MUTYH Y179C	Most common pathogenic MUTYH variant; biallelic carriers develop MUTYH-Associ...	Cancer Risk	Base Excision Repair	Established
rs36053993	MUTYH G396D	Second most common pathogenic MUTYH variant; biallelic carriers develop MUTYH...	Cancer Risk	Base Excision Repair	Established
rs804279	GATA4 GATA4/NEIL2 PCOS Susceptibility	Intergenic variant at the GATA4/NEIL2 locus on chromosome 8p23.1 associated w...	Fertility & Ovarian Function	Base Excision Repair	Moderate