Tag

Crohn's Disease

5 genetic variants with this tag.

RSID	Gene	Description	Category
rs3197999	MST1 R689C	Macrophage-stimulating protein variant affecting innate immune response and I...	Immune & Gut	Immune & Gut IBD Innate Immunity	Strong
rs4077515	CARD9 S12N	Gain-of-function missense variant in the CARD9 adaptor protein that enhances ...	Immune & Gut	Immune & Gut Innate Immunity Gut Microbiome	Strong
rs116855232	NUDT15 Arg139Cys	Nucleotide diphosphatase that inactivates toxic thiopurine metabolites; reduc...	Pharmacogenomics	Drug Metabolism Pharmacogenomics Chemotherapy	Established
rs10758669	JAK2	Intergenic variant near JAK2 that increases JAK2 expression and JAK-STAT sign...	Immune & Gut	Immune & Gut Gut Barrier IBD	Strong
rs11362	DEFB1 G-20A	5' UTR variant in the beta-defensin 1 gene that reduces antimicrobial peptide...	Immune & Gut	Innate Immunity Gut Health Immune & Gut	Moderate