Tag

Estrogen Metabolism

8 genetic variants with this tag.

RSID	Gene	Description	Category
rs1238574	SULT1E1 SULT1E1 intronic variant	Intronic variant in SULT1E1 (estrogen sulfotransferase) associated with alter...	Reproductive Hormones	Estrogen Metabolism	Emerging
rs1056836	CYP1B1 Leu432Val	Phase I detoxification enzyme that hydroxylates estradiol to potentially geno...	Methylation & Detox	Estrogen Metabolism	Moderate
rs2046210	ESR1 ESR1 rs2046210	Promoter-region variant upstream of estrogen receptor alpha (ESR1) at 6q25.1;...	Endometriosis & Uterine Health	Estrogen Metabolism	Strong
rs4775936	CYP19A1 CYP19A1 Promoter Region Variant (Aro1)	Regulatory variant in the CYP19A1 aromatase gene that alters estrogen biosynt...	Reproductive Hormones	Estrogen Metabolism	Moderate
rs727479	CYP19A1	Intronic eQTL variant in the aromatase gene CYP19A1; the minor C allele is th...	Reproductive Hormones	Estrogen Metabolism	Strong
rs28936700	CYP1B1 Gly61Glu (G61E)	Pathogenic missense variant in the cytochrome P450 1B1 enzyme that abolishes ...	Vascular Inflammation & Remodeling	Estrogen Metabolism	Established
rs6557160	CCDC170/ESR1	Intergenic 6q25.1 variant between CCDC170 and ESR1; the C allele is an eQTL f...	Endometriosis & Uterine Health	Estrogen Metabolism	Strong
rs73625113	ESR1 ESR1 rs73625113	An intronic regulatory variant in ESR1 at the 6q25.1 locus identified as a hi...	Endometriosis & Uterine Health	Estrogen Metabolism	Strong