Tag

Fibrinolysis

13 genetic variants with this tag.

RSID	Gene	Description	Category
rs11220465	ST3GAL4 ST3GAL4 VWF/FVIII Modifier	Common intronic variant in the ST3GAL4 sialyltransferase gene associated with...	Coronary Artery Disease & Atherosclerosis	Fibrinolysis	Moderate
rs13412535	SERPINE2	Intronic regulatory variant in SERPINE2 that modulates expression of Protease...	Coagulation & Clotting Factors	Fibrinolysis	Strong
rs1799889	SERPINE1 PAI-1 4G/5G Promoter	Promoter insertion/deletion polymorphism that controls PAI-1 (plasminogen act...	Coagulation & Clotting Factors	Fibrinolysis	Strong
rs2731672	F12	Regulatory tag variant in the Factor XII locus associated with plasma FXII ac...	Coagulation & Clotting Factors	Fibrinolysis	Strong
rs4220	FGB Arg448Lys (R448K)	Missense variant in the fibrinogen beta chain that elevates circulating fibri...	Coagulation & Clotting Factors	Fibrinolysis	Moderate
rs5985	F13A1 Val34Leu	Missense variant in Factor XIII A subunit; the Leu34 allele accelerates throm...	Coagulation & Clotting Factors	Fibrinolysis	Strong
rs6050	FGA Thr312Ala	Missense variant in the fibrinogen alpha chain (FGA) that substitutes alanine...	Coagulation & Clotting Factors	Fibrinolysis	Strong
rs41276738	VWF p.Arg854Gln (R854Q) type 2N	Missense variant in the VWF D' domain that abolishes high-affinity Factor VII...	Von Willebrand & Anticoagulant Proteins	Fibrinolysis	Established
rs35257264	ST3GAL4	Intronic variant near ST3GAL4 that modulates VWF and Factor VIII sialylation,...	Coronary Artery Disease & Atherosclerosis	Fibrinolysis	Strong
rs4252130	PLG PLG promoter/intronic variant	Intronic PLG variant tagging a regional haplotype that reduces plasminogen ex...	Innate Immunity & Infection Defense	Fibrinolysis	Moderate
rs4252185	PLG	Intronic PLG variant (intron 1) whose C allele is enriched in Europeans and a...	Innate Immunity & Infection Defense	Fibrinolysis	Emerging
rs6797312	SERPINI1	Intronic variant in the neuroserpin gene; the A allele has been associated wi...	Coronary Artery Disease & Atherosclerosis	Fibrinolysis	Emerging
rs73015965	PLG Lys38Glu (K38E)	Missense variant in plasminogen that reduces fibrinolytic activity and impair...	Innate Immunity & Infection Defense	Fibrinolysis	Strong