Tag

Gut Microbiome

16 genetic variants with this tag.

RSID	Gene	Description	Category
rs10516487	BANK1 R61H	BANK1 scaffold protein missense variant that shifts B-cell receptor signaling...	B-Cell Immunity & Antibody-Mediated Disease	Gut Microbiome	Strong
rs104895431	NOD2	Rare NOD2 missense variant (Ser431Leu) that reduces NF-κB activation in respo...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs104895467	NOD2 NOD2 N852S	Rare NOD2 missense variant (Asn852Ser) that impairs innate immune sensing of ...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs11209026	IL23R R381Q	Strongly protective variant against inflammatory bowel disease and other auto...	IBD & Mucosal Immunity	Gut Microbiome	Established
rs13107325	SLC39A8 A391T	Zinc and manganese transporter variant that reduces metal ion absorption, aff...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs2066844	NOD2 R702W	Missense variant in the NOD2 gene that increases Crohn's disease risk, partic...	IBD & Mucosal Immunity	Gut Microbiome	Established
rs2066845	NOD2 G908R	NOD2 bacterial sensor variant that increases Crohn's disease risk by impairin...	IBD & Mucosal Immunity	Gut Microbiome	Established
rs2075570	MUC1 Near gene	MTX1 intronic variant at 1q22 tagging a gastric cancer susceptibility locus t...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs2241879	ATG16L1	Intronic ATG16L1 variant in tight LD with the T300A coding variant; the G ris...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs2241880	ATG16L1 T300A	Autophagy gene variant affecting bacterial clearance in gut epithelial cells,...	IBD & Mucosal Immunity	Gut Microbiome	Established
rs3832024	FMO3 FMO3 c.591_592del	A 2-bp frameshift deletion in FMO3 that creates a premature stop codon at pos...	Vitamins & Nutrient Absorption	Gut Microbiome	Established
rs4072037	MUC1	Mucin-1 gene variant affecting gastric mucus barrier function and H. pylori c...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs4077515	CARD9 S12N	Gain-of-function missense variant in the CARD9 adaptor protein that enhances ...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs492602	FUT2 FUT2 secretor status proxy	A synonymous FUT2 proxy variant in strong LD with the W143X nonsense allele (...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs516246	FUT2 FUT2 rs516246	Intronic FUT2 proxy variant tagging secretor status — whether ABO blood group...	IBD & Mucosal Immunity	Gut Microbiome	Strong
rs78060698	FUT6	Intronic regulatory variant in FUT6 that alters HNF4α binding and fucosyltran...	Vitamins & Nutrient Absorption	Gut Microbiome	Moderate