Tag

Immune Defense

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs146906133	FRMD5 FRMD5 UTI susceptibility variant	Intronic variant in FRMD5 — a cell-adhesion scaffolding gene — where the rare...	Innate Immunity & Infection Defense	Immune Defense	Emerging
rs1871534	SLC39A4 Leu372Val	Common missense variant in the primary intestinal zinc transporter ZIP4; the ...	Vitamins & Nutrient Absorption	Immune Defense	Strong
rs2976388	PSCA PSCA bladder urothelial variant	Intronic PSCA variant that tags a regulatory region active in bladder urothel...	Innate Immunity & Infection Defense	Immune Defense	Strong
rs3738198	SLC30A1 ZnT1 variant	Intronic variant in the ZnT1 zinc efflux transporter gene; the minor C allele...	Iron & Mineral Transport	Immune Defense	Emerging
rs35947132	PRF1 A91V	Common perforin variant that reduces cytolytic activity by ~50%, acting as a ...	Innate Immunity & Infection Defense	Immune Defense	Strong
rs763780	IL17F His161Arg	Missense variant that reduces IL-17F bioactivity and acts as a natural IL-17F...	TNF, NF-kB & Inflammatory Cytokines	Immune Defense	Moderate
rs7047299	IFNA21	Regulatory variant upstream of interferon alpha-21 associated with increased ...	Innate Immunity & Infection Defense	Immune Defense	Moderate
rs73885319	APOL1 G1 S342G	APOL1 G1 kidney disease risk variant — missense change that evolved for trypa...	Cholesterol & Lipoproteins	Immune Defense	Established
rs35699176	ZNF77 ZNF77 Q100*	Nonsense variant truncating ZNF77 at codon 100, impairing bronchial epithelia...	Allergy & Atopic Disease	Immune Defense	Emerging