Tag

Kidney Disease

13 genetic variants with this tag.

RSID	Gene	Description	Category
rs11264799	FCRL3	Upstream regulatory variant in FCRL3 with a strong eQTL effect on FCRL3 expre...	B-Cell Immunity & Antibody-Mediated Disease	Kidney Disease	Emerging
rs28647808	ADAMTS13 Pro618Ala	Missense variant in the spacer domain of ADAMTS13 that reduces VWF-cleaving p...	Von Willebrand & Anticoagulant Proteins	Kidney Disease	Moderate
rs4293393	UMOD	UMOD promoter variant affecting uromodulin expression, linked to CKD, salt-se...	Uric Acid & Kidney Function	Kidney Disease	Established
rs505802	SLC22A12	Upstream regulatory variant in the URAT1 urate reabsorption transporter gene;...	Uric Acid & Kidney Function	Kidney Disease	Established
rs7151526	SERPINA1	Regulatory variant downstream of SERPINA1 associated with increased susceptib...	B-Cell Immunity & Antibody-Mediated Disease	Kidney Disease	Moderate
rs73885316	APOL1 p.N264K	Protective missense modifier in APOL1 that abolishes G2 risk allele cytotoxic...	Uric Acid & Kidney Function	Kidney Disease	Strong
rs7951	C3	Synonymous C3 variant associated with reduced serum complement C3 levels and ...	B-Cell Immunity & Antibody-Mediated Disease	Kidney Disease	Moderate
rs77924615	UMOD PDILT-UMOD regulatory variant	Intronic regulatory variant physically located in PDILT that controls uromodu...	Uric Acid & Kidney Function	Kidney Disease	Strong
rs62408925	NCK1	Intergenic regulatory variant near NCK1 at 3q22.3; in strong linkage disequil...	Appetite & Obesity	Kidney Disease	Moderate
rs193922485	HNF1B	Rare HNF1B splice-region intronic variant of uncertain significance, found ne...	Blood Sugar & Diabetes	Kidney Disease	Emerging
rs60910145	APOL1 G1 I384M	Second component of the APOL1 G1 kidney disease risk haplotype — a missense v...	Cholesterol & Lipoproteins	Kidney Disease	Established
rs71785313	APOL1 G2 (del388N389Y)	Six-base-pair in-frame deletion removing two amino acids from apolipoprotein ...	Cholesterol & Lipoproteins	Kidney Disease	Established
rs73885319	APOL1 G1 S342G	APOL1 G1 kidney disease risk variant — missense change that evolved for trypa...	Cholesterol & Lipoproteins	Kidney Disease	Established