Tag

Pigmentation

7 genetic variants with this tag.

RSID	Gene	Description	Category
rs1408799	TYRP1 Intron variant	Intronic variant in the eumelanin enzyme TYRP1 associated with eye and hair c...	Skin & Eyes	Pigmentation	Strong
rs16891982	SLC45A2 L374F	Major determinant of light skin pigmentation in Europeans; lighter-skinned in...	Skin & Eyes	Pigmentation	Established
rs1800407	OCA2 Arg419Gln	Eye color modifier gene influencing green and hazel eye color through melanos...	Skin & Eyes	Pigmentation	Strong
rs1805007	MC1R R151C	Strongest "R" allele in the melanocortin-1 receptor, shifting pigment from ph...	Skin & Eyes	Pigmentation	Established
rs201227603	HPS3 HPS3 Splice Donor Variant	Splice donor variant in HPS3 that disrupts exon 5 inclusion, causing Hermansk...	Innate Immunity & Infection Defense	Pigmentation	Established
rs28777	SLC45A2	Intronic pigmentation variant in SLC45A2 strongly associated with skin color,...	Skin & Eyes	Pigmentation	Established
rs6058017	ASIP A8818G	3'UTR variant controlling ASIP protein output; G allele reduces ASIP mRNA 12-...	Skin & Eyes	Pigmentation	Moderate