Tag

Respiratory Infections

16 genetic variants with this tag.

RSID	Gene	Description	Category
rs10399931	CHI3L1 CHI3L1 eQTL Partner Variant	Upstream regulatory variant in the CHI3L1 YKL-40 quantitative trait locus; th...	Allergy & Atopic Disease	Respiratory Infections	Moderate
rs10849448	LTBR	Regulatory variant in the lymphotoxin beta receptor gene associated with incr...	Innate Immunity & Infection Defense	Respiratory Infections	Strong
rs114947103	CDHR3 CDHR3 intronic variant	Intronic CDHR3 variant in high linkage disequilibrium with the C529Y function...	Innate Immunity & Infection Defense	Respiratory Infections	Moderate
rs12252	IFITM3 IFITM3 rs12252 (c.42T>C)	Splice-region synonymous variant in the innate antiviral gene IFITM3; the G a...	Innate Immunity & Infection Defense	Respiratory Infections	Strong
rs1800450	MBL2 Gly54Asp (variant B)	Missense variant disrupting mannose-binding lectin oligomerization, reducing ...	Innate Immunity & Infection Defense	Respiratory Infections	Strong
rs11650680	ORMDL3 ORMDL3 17q21 asthma susceptibility	Intronic regulatory variant in the ORMDL3 17q21 haploblock; the C allele driv...	Allergy & Atopic Disease	Respiratory Infections	Strong
rs12551256	IL33 IL33 protective asthma variant	Intronic IL33 variant where the G allele is negatively associated with asthma...	Allergy & Atopic Disease	Respiratory Infections	Emerging
rs397515563	DNAI1 DNAI1 IVS19+1G>A	Splice donor variant disrupting DNAI1 intron 19, causing in-frame deletion of...	Innate Immunity & Infection Defense	Respiratory Infections	Strong
rs2305480	GSDMB GSDMB Pro311Ser protective haplotype	Missense variant in gasdermin B that increases GSDMB expression and pyroptoti...	Allergy & Atopic Disease	Respiratory Infections	Strong
rs2602899	ADH5 ADH5 Promoter NF-kB Variant	Regulatory SNP in the ADH5 promoter at a potential NF-kB binding site; the pr...	Allergy & Atopic Disease	Respiratory Infections	Moderate
rs35699176	ZNF77 ZNF77 Q100*	Nonsense variant truncating ZNF77 at codon 100, impairing bronchial epithelia...	Allergy & Atopic Disease	Respiratory Infections	Emerging
rs3771166	IL1RL1/IL18R1	GABRIEL Consortium lead GWAS SNP at the IL1RL1/IL18R1 locus on chromosome 2q1...	Allergy & Atopic Disease	Respiratory Infections	Strong
rs4950928	CHI3L1 YKL-40 Promoter Variant (-131C>G)	Promoter variant controlling YKL-40 (chitinase 3-like 1) expression; the comm...	Allergy & Atopic Disease	Respiratory Infections	Strong
rs6967330	CDHR3 C529Y	Missense variant in the rhinovirus-C receptor CDHR3 that increases cell-surfa...	Allergy & Atopic Disease	Respiratory Infections	Strong
rs7216389	GSDMB ORMDL3 17q21 asthma risk	Intronic GSDMB variant that acts as an eQTL for ORMDL3; the T allele elevates...	Allergy & Atopic Disease	Respiratory Infections	Established
rs950881	IL1RL1 IL1RL1 intronic variant	Intronic variant in the IL1RL1 gene on chromosome 2q12 encoding the ST2 recep...	Allergy & Atopic Disease	Respiratory Infections	Moderate