Tag

Sun Sensitivity

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs16891982	SLC45A2 L374F	Major determinant of light skin pigmentation in Europeans; lighter-skinned in...	Skin & Eyes	Pigmentation Melanoma Risk Sun Sensitivity	Established
rs12203592	IRF4 T allele	Regulatory variant in IRF4 enhancer affecting melanocyte pigmentation, sun se...	Skin & Eyes	Skin, Hair & Pigmentation Sun Sensitivity Melanoma	Strong
rs1042602	TYR S192Y	Common tyrosinase variant affecting melanin production, skin pigmentation, ta...	Skin & Eyes	Skin Pigmentation Melanoma Sun Sensitivity	Strong
rs1426654	SLC24A5 Ala111Thr	Sodium/potassium/calcium exchanger that regulates melanin production in skin ...	Skin & Eyes	Skin Pigmentation Ancestry Vitamin D	Established
rs1805007	MC1R R151C	Strongest "R" allele in the melanocortin-1 receptor, shifting pigment from ph...	Skin & Eyes	Pain Sensitivity Skin Health Anesthesia	Established
rs1408799	TYRP1 Intron variant	Intronic variant in the eumelanin enzyme TYRP1 associated with eye and hair c...	Skin & Eyes	Pigmentation Eye Color Sun Sensitivity	Strong
rs6058017	ASIP A8818G	3'UTR variant controlling ASIP protein output; G allele reduces ASIP mRNA 12-...	Skin & Eyes	Pigmentation Melanoma Risk Sun Sensitivity	Moderate
rs12350739	BNC2 Regulatory variant	Intergenic enhancer variant controlling BNC2 expression in melanocytes; deter...	Skin & Eyes	Skin Pigmentation Freckling UV Sensitivity	Strong
rs28777	SLC45A2	Intronic pigmentation variant in SLC45A2 strongly associated with skin color,...	Skin & Eyes	Pigmentation Melanoma Risk Sun Sensitivity	Established