Tag

Adipogenesis

44 genetic variants with this tag.

RSID	Gene	Description	Category
rs1044471	ADIPOR2 ADIPOR2 3'UTR variant	A common 3'UTR variant in the liver-expressed adiponectin receptor 2 gene; th...	Fat Storage & Energy	Adipogenesis	Moderate
rs1058322	ADIPOR2	Intronic ADIPOR2 variant whose T allele reduces receptor expression in immune...	Fat Storage & Energy	Adipogenesis	Moderate
rs1063537	ADIPOQ	3'UTR variant in ADIPOQ that modulates adiponectin mRNA stability; the common...	Fat Storage & Energy	Adipogenesis	Moderate
rs10838738	MTCH2	Intronic GWAS obesity variant in MTCH2 — affects mitochondrial energy balance...	Appetite & Obesity	Adipogenesis	Moderate
rs10848554	ADIPOR2	Intronic ADIPOR2 variant co-associated with cardiovascular disease risk in in...	Fat Storage & Energy	Adipogenesis	Moderate
rs10865710	PPARG PPARG C-681G	PPARG promoter-region enhancer variant that reduces PPARgamma expression, inc...	Fat Storage & Energy	Adipogenesis	Moderate
rs10882283	RBP4 RBP4 rs10882283	5' UTR variant in RBP4 that influences expression of retinol binding protein ...	Fat Storage & Energy	Adipogenesis	Moderate
rs11061937	ADIPOR2 ADIPOR2 rs11061937	Intronic ADIPOR2 variant associated with cardiovascular disease risk in indiv...	Fat Storage & Energy	Adipogenesis	Moderate
rs1151996	PPARG PPARG rs1151996	Intronic PPARG variant significantly associated with circulating vitamin D le...	Fat Storage & Energy	Adipogenesis	Moderate
rs1152003	PPARG	PPARG 3'-flanking region variant — the G allele independently tags a PPARG re...	Fat Storage & Energy	Adipogenesis	Emerging
rs1175543	PPARG PPARG rs1175543	Intronic PPARG variant in strong linkage disequilibrium with rs709158; the G ...	Fat Storage & Energy	Adipogenesis	Emerging
rs1175544	PPARG PPARG rs1175544	Intronic PPARG variant that accounts for ~7% of individual variation in body ...	Fat Storage & Energy	Adipogenesis	Emerging
rs12094543	ZMYM4 ZMYM4 rs12094543	Intronic variant in ZMYM4, a chromatin-remodeling transcription factor whose ...	Fat Storage & Energy	Adipogenesis	Emerging
rs12490265	PPARG PPARG Intronic Haplotype Variant	Intronic PPARG variant in a metabolic syndrome–associated haplotype block; th...	Fat Storage & Energy	Adipogenesis	Emerging
rs12636454	PPARG PPARG rs12636454	Intronic PPARG variant associated with modest reduction in type 2 diabetes ri...	Fat Storage & Energy	Adipogenesis	Emerging
rs16861194	ADIPOQ -11426A>G	Upstream promoter variant that reduces ADIPOQ transcription, lowering circula...	Fat Storage & Energy	Adipogenesis	Moderate
rs16861205	ADIPOQ	Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is...	Fat Storage & Energy	Adipogenesis	Moderate
rs29941	KCTD15	GWAS obesity locus near KCTD15 — modulates adipogenesis through AP-2 transcri...	Appetite & Obesity	Adipogenesis	Moderate
rs16928751	ADIPOR2 ADIPOR2 CVD co-association variant	Synonymous coding variant in ADIPOR2 (Q265Q) that was co-associated with card...	Fat Storage & Energy	Adipogenesis	Emerging
rs17036314	PPARG	Intronic PPARG variant — carriers of the C allele have elevated fasting gluco...	Fat Storage & Energy	Adipogenesis	Moderate
rs1797912	PPARG PPARG intronic haplotype variant	Intronic PPARG variant in the same haplotype block as rs1175543; the C allele...	Fat Storage & Energy	Adipogenesis	Emerging
rs1801282	PPARG Pro12Ala	Insulin sensitivity - affects how well your cells respond to insulin	Fat Storage & Energy	Adipogenesis	Established
rs182052	ADIPOQ ADIPOQ promoter -10066A>G	Intronic/promoter-region ADIPOQ variant where the A allele reduces circulatin...	Fat Storage & Energy	Adipogenesis	Strong
rs2241767	ADIPOQ +349A>G	Intronic variant in the adiponectin gene associated with lower circulating ad...	Fat Storage & Energy	Adipogenesis	Moderate
rs2279525	PPARGC1A PPARGC1A 3' UTR metabolic association variant	3' UTR variant in the PGC-1alpha gene that may alter PPARGC1A mRNA stability ...	Fat Storage & Energy	Adipogenesis	Emerging
rs6947337	INHBA	Activin A signaling variant near INHBA linking adipocyte dysfunction to share...	Appetite & Obesity	Adipogenesis	Moderate
rs2920502	PPARG PPARG rs2920502	Intronic PPARG variant associated with body fat percentage, impaired glucose ...	Fat Storage & Energy	Adipogenesis	Moderate
rs2959272	PPARG PPARG intronic calorie-restriction trial variant	Intronic PPARG variant significantly associated with individual variation in ...	Fat Storage & Energy	Adipogenesis	Emerging
rs358806	WNT5A	Regulatory variant near WNT5A linked to type 2 diabetes risk via impaired Wnt...	Fat Storage & Energy	Adipogenesis	Moderate
rs3211883	CD36	Intronic CD36 variant associated with altered body adiposity and platelet CD3...	Triglycerides & Fatty Acids	Adipogenesis	Moderate
rs3745012	LPIN2 LPIN2 3'UTR variant	3' UTR regulatory variant in LPIN2 (lipin 2) that alters fat distribution and...	Fat Storage & Energy	Adipogenesis	Moderate
rs3774261	ADIPOQ ADIPOQ rs3774261	Intronic ADIPOQ variant that reduces circulating adiponectin levels in G alle...	Fat Storage & Energy	Adipogenesis	Moderate
rs3856806	PPARG His477His (C1431T)	Synonymous PPARG variant where the T allele reduces type 2 diabetes risk and ...	Fat Storage & Energy	Adipogenesis	Strong
rs4684847	PPARG PPARG cis-regulatory variant (PR domain recruitment)	Intronic cis-regulatory PPARG variant where the C allele recruits PR domain r...	Fat Storage & Energy	Adipogenesis	Moderate
rs4684854	PPARG	Intergenic regulatory variant downstream of PPARG associated with central obe...	Fat Storage & Energy	Adipogenesis	Emerging
rs367643250	DYRK1B R102C	Rare gain-of-function variant causing autosomal dominant metabolic syndrome (...	Blood Sugar & Diabetes	Adipogenesis	Strong
rs4783244	CDH13	Intronic CDH13 variant altering T-cadherin expression; T allele carriers have...	Triglycerides & Fatty Acids	Adipogenesis	Strong
rs6809631	PPARG	Intronic PPARG promoter tagSNP associated with modest reduction in type 2 dia...	Fat Storage & Energy	Adipogenesis	Emerging
rs6954668	SFRP5 SFRP5 Wnt5a inhibitor variant	Intergenic variant near the SFRP5 adipokine locus; the A allele is strongly e...	Fat Storage & Energy	Adipogenesis	Emerging
rs709158	PPARG	Intronic PPARG variant in strong linkage disequilibrium with rs1175543; the G...	Fat Storage & Energy	Adipogenesis	Emerging
rs7649970	PPARG PPARG C-689T	PPARG PPARγ2 P2 promoter variant that reduces basal promoter activity, elevat...	Fat Storage & Energy	Adipogenesis	Moderate
rs822391	ADIPOQ IVS1+407C>T	Intronic variant in the adiponectin gene associated with circulating adiponec...	Fat Storage & Energy	Adipogenesis	Moderate
rs9491696	RSPO3	Intronic enhancer variant in RSPO3 that increases gene expression in adipocyt...	Fat Storage & Energy	Adipogenesis	Strong
rs9817428	PPARG PPARG promoter tagSNP	Intronic PPARG tagSNP with cross-ethnic replication for type 2 diabetes risk ...	Fat Storage & Energy	Adipogenesis	Emerging