Tag

Anxiety

24 genetic variants with this tag.

RSID	Gene	Description	Category
rs1006737	CACNA1C	L-type calcium channel gene variant affecting mood regulation, emotional proc...	Mood & Behavior	Anxiety	Strong
rs1049353	CNR1 3'UTR (G1359A)	Synonymous exon 4 variant in the cannabinoid receptor 1 gene; near an exon sp...	Mood & Behavior	Anxiety	Moderate
rs10786831	SORCS3 SORCS3 Depression Variant	Intronic variant in the neurotrophin sorting receptor SORCS3, the top GWAS hi...	Mood & Behavior	Anxiety	Strong
rs10947690	MDGA1 Leu61Pro	Missense variant in the inhibitory synapse regulator MDGA1 that impairs neuro...	Hormones & Sleep	Anxiety	Strong
rs11599236	SORCS3 SORCS3 Neurotrophin Sorting	Intronic variant in the BDNF-receptor trafficking gene SORCS3, associated wit...	Mood & Behavior	Anxiety	Strong
rs12624433	SLC12A5 KCC2 Chloride Transport	Intronic variant in SLC12A5 reducing KCC2 potassium-chloride cotransporter fu...	Mood & Behavior	Anxiety	Moderate
rs2271933	HCRTR1 Ile408Val	Missense variant in the orexin/hypocretin receptor 1 that alters G-protein si...	Mood & Behavior	Anxiety	Moderate
rs2371365	PCLO PCLO Presynaptic Scaffold	Intronic variant in the presynaptic scaffold gene PCLO linked to altered mono...	Mood & Behavior	Anxiety	Moderate
rs25531	SLC6A4 A>G	Promoter SNP near 5-HTTLPR that modifies serotonin transporter expression and...	Mood & Behavior	Anxiety	Moderate
rs279858	GABRA2 K132K	GABA-A receptor alpha-2 subunit variant affecting alcohol response, anxiety, ...	Mood & Behavior	Anxiety	Strong
rs324420	FAAH Pro129Thr	Affects anandamide levels through altered FAAH enzyme stability, influencing ...	Mood & Behavior	Anxiety	Strong
rs34579341	NEGR1 NEGR1 Neuronal Growth Regulator	Intronic tag SNP in NEGR1 affecting neuronal cell adhesion, hippocampal neuro...	Mood & Behavior	Anxiety	Strong
rs41423247	NR3C1 BclI	Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s...	Mood & Behavior	Anxiety	Strong
rs4395923	CYP7B1 CYP7B1 Neurosteroid Hydroxylase	Intronic variant in the brain neurosteroid hydroxylase gene affecting DHEA an...	Mood & Behavior	Anxiety	Emerging
rs4570625	TPH2 G-703T	Promoter variant affecting brain serotonin synthesis enzyme; influences emoti...	Mood & Behavior	Anxiety	Moderate
rs4702	FURIN proBDNF Processing Variant	A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si...	Mood & Behavior	Anxiety	Moderate
rs228697	PER3 Pro864Ala	Core clock gene variant that shifts circadian period length and influences mo...	Hormones & Sleep	Anxiety	Moderate
rs72704544	GPM6A GPM6A Neuronal Membrane Glycoprotein	Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do...	Mood & Behavior	Anxiety	Moderate
rs4855559	MYH15	Intronic variant in the myosin heavy chain 15 gene associated with impaired c...	Cardiomyopathy & Structural Heart	Anxiety	Emerging
rs73034295	IGSF9B IGSF9B Inhibitory Synapse Adhesion	Intronic variant in the gene encoding the inhibitory synaptic adhesion protei...	Mood & Behavior	Anxiety	Emerging
rs324981	NPSR1 Asn107Ile	Gain-of-function missense variant in the neuropeptide S receptor that increas...	Hormones & Sleep	Anxiety	Moderate
rs9556979	STK24 HPA Axis Regulation	Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur...	Mood & Behavior	Anxiety	Moderate
rs4746	GLO1 Glu111Ala	Missense variant in glyoxalase 1 reducing enzyme activity, allowing methylgly...	Hormones & Sleep	Anxiety	Moderate
rs5751876	ADORA2A 1976T>C	Adenosine A2A receptor variant that determines individual sensitivity to caff...	Hormones & Sleep	Anxiety	Strong