Tag
Cancer Screening
11 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs17879961 | CHEK2 I157T | Missense variant in the CHEK2 FHA domain that impairs phosphoprotein binding ... | Cancer Risk | Strong | |
| rs10848087 | PIWIL1 PIWIL1 G>A (c.1128G>A) | Synonymous variant in PIWIL1 associated with increased epithelial ovarian can... | Fertility & Ovarian Function | Emerging | |
| rs1799793 | ERCC2 D312N | Missense variant in the XPD helicase that reduces nucleotide excision repair ... | Cancer Risk | Strong | |
| rs1799950 | BRCA1 Q356R | Common missense variant near the BRCA1 RING finger domain; classified as beni... | Cancer Risk | Moderate | |
| rs1800734 | MLH1 -93G>A | Promoter variant in the MLH1 DNA mismatch repair gene that reduces transcript... | Cancer Risk | Strong | |
| rs1867277 | FOXE1 c.-283G>A | Functional 5' UTR variant in the FOXE1 thyroid transcription factor that incr... | Cancer Risk | Strong | |
| rs2228000 | XPC Ala499Val | Missense variant in the DNA damage recognition gene XPC that moderately reduc... | Cancer Risk | Moderate | |
| rs2279744 | MDM2 SNP309 T>G | Regulatory variant in the MDM2 promoter that increases Sp1 transcription fact... | Cancer Risk | Strong | |
| rs25487 | XRCC1 R399Q | Base excision repair scaffold protein that coordinates repair of oxidative DN... | Cancer Risk | Strong | |
| rs6983267 | 8q24 | Intergenic enhancer variant near MYC oncogene — modestly increases colorectal... | Cancer Risk | Established | |
| rs4975605 | TERT | Intronic TERT variant influencing telomere maintenance, associated with testi... | Longevity & Aging | Moderate |