Tag
Depression
13 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1006737 | CACNA1C | L-type calcium channel gene variant affecting mood regulation, emotional proc... | Mood & Behavior | Strong | |
| rs10514299 | TMEM161B-MEF2C TMEM161B-MEF2C intergenic variant | Intronic variant near the MEF2C transcription factor locus associated with in... | Mood & Behavior | Strong | |
| rs10786831 | SORCS3 SORCS3 Depression Variant | Intronic variant in the neurotrophin sorting receptor SORCS3, the top GWAS hi... | Mood & Behavior | Strong | |
| rs1743963 | SGK1 | Intronic SGK1 variant associated with depression susceptibility in coronary h... | Blood Pressure & Hypertension | Emerging | |
| rs1360780 | FKBP5 Intronic C>T | Co-chaperone of the glucocorticoid receptor that regulates cortisol feedback ... | Mood & Behavior | Strong | |
| rs1545843 | SLC6A15 SLC6A15 depression risk variant | Variant reducing SLC6A15 expression in hippocampus; AA carriers show increase... | Mood & Behavior | Strong | |
| rs2815752 | NEGR1 | Top obesity GWAS variant near NEGR1 | Appetite & Obesity | Strong | |
| rs139315125 | PER3 H417R | Rare PER3 missense variant that co-occurs on the FASPS3 haplotype with Pro415... | Hormones & Sleep | Strong | |
| rs2522833 | PCLO Ser4814Ala | Missense variant in the C2A calcium-binding domain of presynaptic scaffolding... | Mood & Behavior | Moderate | |
| rs4570625 | TPH2 G-703T | Promoter variant affecting brain serotonin synthesis enzyme; influences emoti... | Mood & Behavior | Moderate | |
| rs2675703 | OPN4 | Missense variant (Pro10Leu) in melanopsin, the photopigment driving circadian... | Hormones & Sleep | Emerging | |
| rs4702 | FURIN proBDNF Processing Variant | A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si... | Mood & Behavior | Moderate | |
| rs6323 | MAOA R297R | X-linked monoamine oxidase A variant affecting enzyme activity and neurotrans... | Mood & Behavior | Strong |