Tag

Environmental Toxins

7 genetic variants with this tag.

RSID	Gene	Description	Category
rs2032582	ABCB1 G2677T/A (Ser893Ala/Thr)	Triallelic missense variant in the P-glycoprotein efflux pump that reduces th...	Gamete Quality & DNA Repair	Environmental Toxins	Moderate
rs1154404	ADH5 ADH5 Asthma Risk Haplotype Variant	Intronic variant in ADH5 (GSNOR) in near-complete LD (r²=0.99) with adjacent ...	Allergy & Atopic Disease	Environmental Toxins	Moderate
rs2070676	CYP2E1	Intronic CYP2E1 variant tagging the *1B haplotype; C allele marks reduced CYP...	Pharmacogenomics	Environmental Toxins	Moderate
rs2480256	CYP2E1	3' UTR variant that increases CYP2E1 expression, raising hepatotoxicity risk ...	Pharmacogenomics	Environmental Toxins	Moderate
rs2515641	CYP2E1	Synonymous exon-8 variant that reduces CYP2E1 mRNA and protein expression, al...	Pharmacogenomics	Environmental Toxins	Moderate
rs4646976	CYP2E1	CYP2E1 intronic haplotype tag — affects enzyme activity and susceptibility to...	Pharmacogenomics	Environmental Toxins	Moderate
rs71748309	GSTT1 Null (Gene Deletion)	Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac...	Methylation & Detox	Environmental Toxins	Strong