Tag

Fat Distribution

19 genetic variants with this tag.

RSID	Gene	Description	Category
rs10195252	GRB14/COBLL1	Intergenic variant between GRB14 and COBLL1 that acts as an eQTL for GRB14 in...	Blood Sugar & Diabetes	Fat Distribution	Strong
rs10852521	FTO	FTO intron 1 variant associated with BMI and body fat accumulation, with stro...	Fitness & Body	Fat Distribution	Moderate
rs150090666	PDE3B PDE3B R783X	Loss-of-function variant in phosphodiesterase 3B — carriers have enhanced cAM...	Triglycerides & Fatty Acids	Fat Distribution	Strong
rs11152221	MC4R MC4R Proximal LD Block Variant	Intergenic variant in the proximal 3' regulatory block near MC4R associated w...	Appetite & Obesity	Fat Distribution	Strong
rs12094543	ZMYM4 ZMYM4 rs12094543	Intronic variant in ZMYM4, a chromatin-remodeling transcription factor whose ...	Fat Storage & Energy	Fat Distribution	Emerging
rs1943226	MC4R MC4R third tagSNP	Upstream regulatory tag variant ~3 kb proximal to MC4R, included in MC4R hapl...	Appetite & Obesity	Fat Distribution	Emerging
rs11705701	IGF2BP2 IGF2BP2 Insulin Signaling Variant	Upstream regulatory variant in IGF2BP2 that shifts mRNA isoform balance in ad...	Blood Sugar & Diabetes	Fat Distribution	Moderate
rs12490265	PPARG PPARG Intronic Haplotype Variant	Intronic PPARG variant in a metabolic syndrome–associated haplotype block; th...	Fat Storage & Energy	Fat Distribution	Emerging
rs2922126	GHSR GHSR A/G (rs2922126)	Upstream regulatory variant near the ghrelin receptor gene; the A allele is a...	Appetite & Obesity	Fat Distribution	Moderate
rs476828	MC4R MC4R-region BMI variant	Intergenic variant in the MC4R regulatory haplotype block, tagging the same a...	Appetite & Obesity	Fat Distribution	Strong
rs1797912	PPARG PPARG intronic haplotype variant	Intronic PPARG variant in the same haplotype block as rs1175543; the C allele...	Fat Storage & Energy	Fat Distribution	Emerging
rs2920502	PPARG PPARG rs2920502	Intronic PPARG variant associated with body fat percentage, impaired glucose ...	Fat Storage & Energy	Fat Distribution	Moderate
rs62623713	SYPL2 E99G	Low-frequency missense variant in SYPL2 associated with morbid obesity suscep...	Fitness & Body	Fat Distribution	Emerging
rs3745012	LPIN2 LPIN2 3'UTR variant	3' UTR regulatory variant in LPIN2 (lipin 2) that alters fat distribution and...	Fat Storage & Energy	Fat Distribution	Moderate
rs4684847	PPARG PPARG cis-regulatory variant (PR domain recruitment)	Intronic cis-regulatory PPARG variant where the C allele recruits PR domain r...	Fat Storage & Energy	Fat Distribution	Moderate
rs4684854	PPARG	Intergenic regulatory variant downstream of PPARG associated with central obe...	Fat Storage & Energy	Fat Distribution	Emerging
rs3787348	PTPN1 PTPN1 intronic variant	Intronic PTPN1 tag SNP within the 100-kb insulin-resistance haplotype block; ...	Blood Sugar & Diabetes	Fat Distribution	Moderate
rs6981587	ANK1 ANK1 small-ankyrin T2D locus variant	Intronic ANK1 variant at the NKX6-3/ANK1 type 2 diabetes locus; the T allele ...	Fat Storage & Energy	Fat Distribution	Moderate
rs587777380	DYRK1B H90P / H90R	Multi-allelic pathogenic locus — both H90P (T>G) and H90R (T>C) disrupt the D...	Blood Sugar & Diabetes	Fat Distribution	Strong