Tag
Gut Health
14 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10063949 | SLC23A1 SLC23A1 variant | Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... | Vitamins & Nutrient Absorption | Moderate | |
| rs104895444 | NOD2 | Rare NOD2 missense variant (Val793Met) identified in IBD deep-resequencing; c... | IBD & Mucosal Immunity | Moderate | |
| rs1050152 | SLC22A4 OCTN1 L503F | Missense variant in SLC22A4 encoding the organic cation/ergothioneine transpo... | Allergy & Atopic Disease | Strong | |
| rs121434290 | SLC39A4 SLC39A4 p.Asn106Lys | Pathogenic missense variant in the ZIP4 intestinal zinc transporter; homozygo... | Iron & Mineral Transport | Established | |
| rs1049742 | AOC1 | Missense variant in the diamine oxidase enzyme that contributes to reduced hi... | Methylation & Detox | Moderate | |
| rs11362 | DEFB1 G-20A | 5' UTR variant in the beta-defensin 1 gene that reduces antimicrobial peptide... | IBD & Mucosal Immunity | Moderate | |
| rs1799724 | TNF -857C>T | TNF promoter variant that disrupts an OCT-1 binding site, altering TNF-alpha ... | TNF, NF-kB & Inflammatory Cytokines | Moderate | |
| rs3024505 | IL10 3' downstream variant | Downstream IL10 enhancer variant that disrupts a STAT3 binding site, reducing... | Interferon Signaling & Systemic Autoimmune | Strong | |
| rs2976388 | PSCA PSCA bladder urothelial variant | Intronic PSCA variant that tags a regulatory region active in bladder urothel... | Innate Immunity & Infection Defense | Strong | |
| rs41380347 | MCM6 G-13915T | East African lactase persistence allele — MCM6 enhancer SNP that independentl... | Vitamins & Nutrient Absorption | Strong | |
| rs4562997 | SMAD3 | Second intronic enhancer variant in SMAD3 that modulates TGF-beta effector si... | IBD & Mucosal Immunity | Moderate | |
| rs17293632 | SMAD3 | Intronic regulatory variant in SMAD3 that alters TGF-beta effector signaling ... | Allergy & Atopic Disease | Strong | |
| rs6908425 | CDKAL1 | Intronic variant in CDKAL1, a tRNA methylthiotransferase gene; the C allele i... | IBD & Mucosal Immunity | Strong | |
| rs6974491 | ELMO1 | Intronic ELMO1 variant acting as an eQTL that modulates engulfment and cell m... | IBD & Mucosal Immunity | Moderate |