Tag

Hormones & Thyroid

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs225014	DIO2 Thr92Ala	Affects conversion of inactive T4 to active T3 thyroid hormone in brain, pitu...	Hormones & Sleep	Hormones & Thyroid Neurotransmitters Metabolism	Strong
rs1799941	SHBG	Promoter region variant affecting sex hormone-binding globulin levels, with t...	Hormones & Sleep	Hormones & Thyroid Cardiovascular Diabetes	Strong
rs523349	SRD5A2 V89L	Missense variant reducing 5-alpha-reductase type 2 enzyme activity, affecting...	Hormones & Sleep	Hormones & Thyroid Testosterone Prostate	Moderate
rs743572	CYP17A1 -34 T>C	Promoter variant affecting 17α-hydroxylase expression and steroid hormone syn...	Hormones & Sleep	Hormones & Thyroid Reproductive Health Steroid Hormones	Strong
rs2234693	ESR1 PvuII	Estrogen receptor alpha intron variant affecting receptor expression and estr...	Hormones & Sleep	Hormones & Thyroid Bone Health Cardiovascular	Moderate
rs1991517	TSHR Asp727Glu	Affects TSH receptor sensitivity and thyroid hormone regulation; influences T...	Hormones & Sleep	Hormones & Thyroid Thyroid Metabolism	Strong
rs944289	FOXE1	Regulatory variant near FOXE1 at 14q13.3 that reduces PTCSC3 tumor suppressor...	Cancer Risk	Thyroid Cancer Risk Hormones & Thyroid	Strong
rs1867277	FOXE1 c.-283G>A	Functional 5' UTR variant in the FOXE1 thyroid transcription factor that incr...	Cancer Risk	Thyroid Cancer Risk Hormones & Thyroid	Strong
rs965513	FOXE1	Strongest GWAS thyroid locus — regulatory variant near FOXE1 affecting thyroi...	Hormones & Sleep	Thyroid Hormones & Thyroid Cancer Risk	Strong