Tag

IBD

5 genetic variants with this tag.

RSID	Gene	Description	Category
rs13361189	IRGM −4299T>C	Autophagy regulator affecting bacterial clearance in the gut and Crohn's dise...	Immune & Gut	Immune & Gut Autophagy IBD	Strong
rs3197999	MST1 R689C	Macrophage-stimulating protein variant affecting innate immune response and I...	Immune & Gut	Immune & Gut IBD Innate Immunity	Strong
rs35829419	NLRP3 Q705K	Gain-of-function missense variant in the NLRP3 inflammasome sensor that eleva...	Immune & Gut	Immune & Gut Inflammation Gout	Moderate
rs116855232	NUDT15 Arg139Cys	Nucleotide diphosphatase that inactivates toxic thiopurine metabolites; reduc...	Pharmacogenomics	Drug Metabolism Pharmacogenomics Chemotherapy	Established
rs10758669	JAK2	Intergenic variant near JAK2 that increases JAK2 expression and JAK-STAT sign...	Immune & Gut	Immune & Gut Gut Barrier IBD	Strong