Tag

Immune & Antiviral

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs114947103	CDHR3 CDHR3 intronic variant	Intronic CDHR3 variant in high linkage disequilibrium with the C529Y function...	Innate Immunity & Infection Defense	Immune & Antiviral	Moderate
rs12252	IFITM3 IFITM3 rs12252 (c.42T>C)	Splice-region synonymous variant in the innate antiviral gene IFITM3; the G a...	Innate Immunity & Infection Defense	Immune & Antiviral	Strong
rs117648444	IFNL4 Pro70Ser (P70S)	Missense variant in IFNL4 exon 2 that reduces IFN-λ4 protein activity; the Se...	Pharmacogenomics	Immune & Antiviral	Strong
rs3077	HLA-DPA1 HLA-DPA1 3′ UTR variant	Regulatory variant in the 3′ UTR of HLA-DPA1 that controls surface expression...	Interferon Signaling & Systemic Autoimmune	Immune & Antiviral	Strong
rs3775291	TLR3 Leu412Phe	Missense variant in TLR3 that halves dsRNA-binding capacity, reducing antivir...	Innate Immunity & Infection Defense	Immune & Antiviral	Strong
rs7770370	HLA-DPB1	Intronic tag SNP in HLA-DPB1 (and upstream of HLA-DPA1) that marks the HLA-DP...	Interferon Signaling & Systemic Autoimmune	Immune & Antiviral	Strong
rs9277535	HLA-DPB1	3' UTR eQTL that reduces HLA-DPB1 expression, impairing antigen presentation ...	Interferon Signaling & Systemic Autoimmune	Immune & Antiviral	Strong
rs368234815	IFNL4 ss469415590 (TT/ΔG)	Causal frameshift polymorphism controlling IFNL4 protein production; the ΔG a...	Pharmacogenomics	Immune & Antiviral	Established
rs6967330	CDHR3 C529Y	Missense variant in the rhinovirus-C receptor CDHR3 that increases cell-surfa...	Allergy & Atopic Disease	Immune & Antiviral	Strong