Tag

Immune Function

6 genetic variants with this tag.

RSID	Gene	Description	Category
rs2066845	NOD2 G908R	NOD2 bacterial sensor variant that increases Crohn's disease risk by impairin...	Immune & Gut	Immune Function Gut Microbiome Inflammatory Bowel Disease	Established
rs2241880	ATG16L1 T300A	Autophagy gene variant affecting bacterial clearance in gut epithelial cells,...	Immune & Gut	Autophagy Diet Immune Function	Established
rs3751143	P2RX7 Glu496Ala	Loss-of-function variant in the P2X7 receptor that reduces inflammatory respo...	Brain & Mental Health	Pain Sensitivity Inflammation Immune Function	Strong
rs208294	P2RX7 His155Tyr	Gain-of-function missense variant in the P2X7 ATP-gated receptor that increas...	Brain & Mental Health	Neuroinflammation Pain Sensitivity Chronic Pain	Moderate
rs1718119	P2RX7 Ala348Thr	Gain-of-function variant in the P2X7 receptor that increases ATP-gated pore f...	Brain & Mental Health	Neuroinflammation Pain Sensitivity Inflammation	Moderate
rs7958311	P2RX7 Arg270His	P2RX7 variant with a unique dual mechanism — gain-of-function in channel open...	Brain & Mental Health	Pain Sensitivity Neuroinflammation Inflammation	Moderate