Tag
Melatonin
8 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs139315125 | PER3 H417R | Rare PER3 missense variant that co-occurs on the FASPS3 haplotype with Pro415... | Hormones & Sleep | Strong | |
| rs184039278 | CRY1 CRY1Δ11 | Splice-site variant in the circadian clock gene CRY1 that causes exon 11 skip... | Hormones & Sleep | Strong | |
| rs2675703 | OPN4 | Missense variant (Pro10Leu) in melanopsin, the photopigment driving circadian... | Hormones & Sleep | Emerging | |
| rs34714364 | APH1A APH1A gamma-secretase variant | Synonymous variant in CA14 near APH1A; T allele is associated with morning ch... | Hormones & Sleep | Moderate | |
| rs3816183 | HAAO Ile37Val | Missense variant in the kynurenine pathway enzyme HAAO that shifts tryptophan... | Hormones & Sleep | Moderate | |
| rs4446909 | ASMT Promoter A>G | Final enzyme in melatonin synthesis; promoter variant reduces ASMT expression... | Hormones & Sleep | Moderate | |
| rs4753426 | MTNR1B | Promoter variant in the melatonin receptor 1B gene that alters MTNR1B express... | Hormones & Sleep | Moderate | |
| rs55694368 | PER2 PER2 regulatory variant | Upstream regulatory signal near the core circadian clock gene PER2 that shift... | Hormones & Sleep | Strong |