Tag

Melatonin

12 genetic variants with this tag.

RSID	Gene	Description	Category
rs10830963	MTNR1B Intron C>G	Melatonin receptor variant that extends nighttime melatonin signaling in panc...	Hormones & Sleep	Melatonin	Established
rs139315125	PER3 H417R	Rare PER3 missense variant that co-occurs on the FASPS3 haplotype with Pro415...	Hormones & Sleep	Melatonin	Strong
rs150812083	PER3 PER3 Pro415Ala (FASPS3)	Rare PER3 missense variant that destabilizes the circadian clock protein, sho...	Hormones & Sleep	Melatonin	Strong
rs17679445	PNPO Arg116Gln	Missense variant in pyridoxamine 5'-phosphate oxidase that reduces the enzyme...	Hormones & Sleep	Melatonin	Moderate
rs184039278	CRY1 CRY1Δ11	Splice-site variant in the circadian clock gene CRY1 that causes exon 11 skip...	Hormones & Sleep	Melatonin	Strong
rs1562444	MTNR1B MTNR1B 3'UTR Melatonin Signaling Variant	Regulatory 3'UTR variant in the melatonin receptor 1B gene that affects MTNR1...	Blood Sugar & Diabetes	Melatonin	Moderate
rs2675703	OPN4	Missense variant (Pro10Leu) in melanopsin, the photopigment driving circadian...	Hormones & Sleep	Melatonin	Emerging
rs34714364	APH1A APH1A gamma-secretase variant	Synonymous variant in CA14 near APH1A; T allele is associated with morning ch...	Hormones & Sleep	Melatonin	Moderate
rs3816183	HAAO Ile37Val	Missense variant in the kynurenine pathway enzyme HAAO that shifts tryptophan...	Hormones & Sleep	Melatonin	Moderate
rs4446909	ASMT Promoter A>G	Final enzyme in melatonin synthesis; promoter variant reduces ASMT expression...	Hormones & Sleep	Melatonin	Moderate
rs4753426	MTNR1B	Promoter variant in the melatonin receptor 1B gene that alters MTNR1B express...	Hormones & Sleep	Melatonin	Moderate
rs55694368	PER2 PER2 regulatory variant	Upstream regulatory signal near the core circadian clock gene PER2 that shift...	Hormones & Sleep	Melatonin	Strong