Tag

Methylation & Detox

14 genetic variants with this tag.

RSID	Gene	Description	Category
rs10483099	QDPR	Intronic variant near QDPR that affects BH4 recycling efficiency, influencing...	Methylation & Detox	Methylation & Detox	Emerging
rs1049742	AOC1	Missense variant in the diamine oxidase enzyme that contributes to reduced hi...	Methylation & Detox	Methylation & Detox	Moderate
rs199971687	MMAB	Pathogenic splice acceptor variant in MMAB that abolishes adenosylcobalamin s...	Vitamins & Nutrient Absorption	Methylation & Detox	Established
rs11683424	DNMT3A	Intronic variant in the de novo DNA methyltransferase DNMT3A, associated with...	Methylation & Detox	Methylation & Detox	Emerging
rs13420827	DNMT3A	3' UTR variant in the de novo DNA methyltransferase DNMT3A, associated with a...	Methylation & Detox	Methylation & Detox	Emerging
rs162036	MTRR K350R (Lys350Arg)	MTRR cobalamin-reactivation variant — reduces B12 recycling efficiency and mo...	Methylation & Detox	Methylation & Detox	Moderate
rs162040	MTRR	Intronic MTRR tag SNP in a haplotype block where the C-allele variant associa...	Methylation & Detox	Methylation & Detox	Emerging
rs17309872	GSS	Downstream regulatory variant of glutathione synthetase (GSS) associated with...	Methylation & Detox	Methylation & Detox	Moderate
rs202720	FOLH1	Intronic variant in the intestinal folate-cleaving enzyme FOLH1 (GCPII); the ...	Methylation & Detox	Methylation & Detox	Emerging
rs326124	MTRR	Intronic MTRR variant associated with colorectal cancer survival in interacti...	Methylation & Detox	Methylation & Detox	Emerging
rs3776467	MTRR	Intronic MTRR variant with sex-specific association with DNA methylation patt...	Methylation & Detox	Methylation & Detox	Emerging
rs3788189	SLC19A1 SLC19A1 IVS2 variant	Intronic variant in the folate transporter gene associated with pemetrexed tr...	Methylation & Detox	Methylation & Detox	Emerging
rs387907200	SPR	Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe...	Methylation & Detox	Methylation & Detox	Strong
rs71748309	GSTT1 Null (Gene Deletion)	Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac...	Methylation & Detox	Methylation & Detox	Strong