|
rs1006737
|
CACNA1C
|
L-type calcium channel gene variant affecting mood regulation, emotional proc...
|
Mood & Behavior
|
|
Strong
|
|
rs10514299
|
TMEM161B-MEF2C
TMEM161B-MEF2C intergenic variant
|
Intronic variant near the MEF2C transcription factor locus associated with in...
|
Mood & Behavior
|
|
Strong
|
|
rs1019385
|
GRIN2B
|
Promoter variant in the GRIN2B Sp1 binding site that reduces NR2B subunit exp...
|
Neurology & Cognition
|
|
Moderate
|
|
rs10786831
|
SORCS3
SORCS3 Depression Variant
|
Intronic variant in the neurotrophin sorting receptor SORCS3, the top GWAS hi...
|
Mood & Behavior
|
|
Strong
|
|
rs11599236
|
SORCS3
SORCS3 Neurotrophin Sorting
|
Intronic variant in the BDNF-receptor trafficking gene SORCS3, associated wit...
|
Mood & Behavior
|
|
Strong
|
|
rs1743963
|
SGK1
|
Intronic SGK1 variant associated with depression susceptibility in coronary h...
|
Blood Pressure & Hypertension
|
|
Emerging
|
|
rs1064395
|
NCAN
|
3' UTR variant in the neurocan gene associated with bipolar disorder and schi...
|
Neurology & Cognition
|
|
Strong
|
|
rs1387923
|
NTRK2
NTRK2/TrkB 3'UTR variant
|
3' UTR variant in the TrkB receptor gene affecting NTRK2 expression; associat...
|
Mood & Behavior
|
|
Moderate
|
|
rs11713169
|
NLGN1
|
Intronic variant in neuroligin 1, a postsynaptic cell adhesion molecule essen...
|
Neurology & Cognition
|
|
Strong
|
|
rs2568958
|
NEGR1
NEGR1 depression/BMI variant
|
Intergenic tag SNP near NEGR1 associated with elevated BMI and major depressi...
|
Mood & Behavior
|
|
Strong
|
|
rs34579341
|
NEGR1
NEGR1 Neuronal Growth Regulator
|
Intronic tag SNP in NEGR1 affecting neuronal cell adhesion, hippocampal neuro...
|
Mood & Behavior
|
|
Strong
|
|
rs35936514
|
LHPP
LHPP depression risk variant
|
Intronic/3'UTR variant in LHPP, a histidine phosphatase essential for stress ...
|
Mood & Behavior
|
|
Strong
|
|
rs17070145
|
WWC1
Intronic C>T
|
Influences episodic memory performance and hippocampal function through the K...
|
Neurology & Cognition
|
|
Moderate
|
|
rs17518584
|
CADM2
|
Intronic CADM2 variant genome-wide significant for information processing spe...
|
Neurology & Cognition
|
|
Moderate
|
|
rs4702
|
FURIN
proBDNF Processing Variant
|
A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si...
|
Mood & Behavior
|
|
Moderate
|
|
rs1906252
|
POU3F2
|
Regulatory variant at chromosome 6q16.1 near POU3F2 (BRN2), a master transcri...
|
Neurology & Cognition
|
|
Strong
|
|
rs72704544
|
GPM6A
GPM6A Neuronal Membrane Glycoprotein
|
Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do...
|
Mood & Behavior
|
|
Moderate
|
|
rs9556979
|
STK24
HPA Axis Regulation
|
Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur...
|
Mood & Behavior
|
|
Moderate
|
|
rs2274319
|
MEF2D
|
Intronic variant in MEF2D encoding a key neuronal transcription factor that r...
|
Neurology & Cognition
|
|
Strong
|
|
rs956572
|
BCL2
|
Intronic variant in the anti-apoptotic gene BCL2 that affects BCL2 expression...
|
Mood & Behavior
|
|
Moderate
|
|
rs4851266
|
AFF3
|
Intronic variant in the super elongation complex gene AFF3; the T allele incr...
|
Neurology & Cognition
|
|
Strong
|
|
rs61734410
|
CACNA1H
Pro640Leu
|
Missense variant in CACNA1H encoding the CaV3.2 T-type calcium channel; the L...
|
Neurology & Cognition
|
|
Moderate
|
|
rs6265
|
BDNF
Val66Met
|
Key neurotrophin variant that controls activity-dependent BDNF release, affec...
|
Neurology & Cognition
|
|
Strong
|
|
rs58194899
|
EIPR1
|
Intronic variant in EIPR1 (endosomal trafficking protein) associated with pai...
|
Pharmacogenomics
|
|
Emerging
|
|
rs6439886
|
CLSTN2
|
Intronic variant in the calsyntenin-2 gene associated with episodic memory pe...
|
Neurology & Cognition
|
|
Moderate
|
|
rs9320913
|
POU3F2
|
Intergenic regulatory variant upstream of POU3F2 (BRN-2), a transcription fac...
|
Neurology & Cognition
|
|
Strong
|