Tag

Pain Medication

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs3892097	CYP2D6 *4	Major enzyme for metabolizing ~25% of medications including opioids, antidepr...	Pharmacogenomics	Drug Metabolism Antidepressants Pain Medication	Established
rs1065852	CYP2D6 *10	Decreased function CYP2D6 variant common in Asian populations	Pharmacogenomics	Drug Metabolism Antidepressants Pain Medication	Established
rs1799853	CYP2C9 *2	Decreased function variant affecting warfarin, phenytoin, and NSAIDs	Pharmacogenomics	Drug Metabolism Warfarin Pain Medication	Established
rs1057910	CYP2C9 *3	No-function CYP2C9 variant with major warfarin implications	Pharmacogenomics	Drug Metabolism Warfarin Pain Medication	Established
rs16947	CYP2D6 *2	Common CYP2D6 variant defining the *2 allele; previously considered normal-fu...	Pharmacogenomics	Pharmacogenomics Drug Metabolism Antidepressants	Strong
rs5030655	CYP2D6 *6	Frameshift deletion causing no enzyme function, defining poor metabolizer sta...	Pharmacogenomics	Drug Metabolism Pain Medication Antidepressants	Established
rs28371725	CYP2D6 *41	Intronic splice variant causing decreased CYP2D6 enzyme activity through aber...	Pharmacogenomics	Drug Metabolism Pharmacogenomics Pain Medication	Established
rs3745274	CYP2B6 516G>T	Decreased-function variant affecting metabolism of efavirenz, methadone, bupr...	Pharmacogenomics	Drug Metabolism Antidepressants Pain Medication	Established
rs1799971	OPRM1 A118G	Mu-opioid receptor variant affecting opioid response, pain sensitivity, and p...	Pharmacogenomics	Drug Metabolism Pain Medication Addiction	Moderate