Tag

Periodontal Disease

8 genetic variants with this tag.

RSID	Gene	Description	Category
rs1047031	DEFB1	3'UTR variant in the beta-defensin 1 gene that disrupts a microRNA binding si...	Dental & Oral Health	Periodontal Disease	Moderate
rs1143627	IL1B -31T>C	Promoter variant that elevates IL-1β transcription, increasing risk of H. pyl...	TNF, NF-kB & Inflammatory Cytokines	Periodontal Disease	Strong
rs1143634	IL1B +3954C>T	Synonymous exon 5 variant in IL-1β that increases IL-1β protein secretion des...	TNF, NF-kB & Inflammatory Cytokines	Periodontal Disease	Strong
rs17561	IL1A Ala114Ser	Missense variant in IL-1α (Ala114Ser) that acts as a common hypomorphic mutat...	TNF, NF-kB & Inflammatory Cytokines	Periodontal Disease	Moderate
rs1360590	CDKN2BAS	Intronic variant in ANRIL at the 9p21.3 locus — the shared susceptibility reg...	Coronary Artery Disease & Atherosclerosis	Periodontal Disease	Moderate
rs2234663	IL1RN	Intron 2 VNTR polymorphism in IL1RN that alters IL-1Ra isoform balance and is...	TNF, NF-kB & Inflammatory Cytokines	Periodontal Disease	Strong
rs4252130	PLG PLG promoter/intronic variant	Intronic PLG variant tagging a regional haplotype that reduces plasminogen ex...	Innate Immunity & Infection Defense	Periodontal Disease	Moderate
rs6596473	SLC23A1 SLC23A1 variant	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Periodontal Disease	Emerging