Tag

Salt Sensitivity

23 genetic variants with this tag.

RSID	Gene	Description	Category
rs1008899	NEDD4L	Intronic NEDD4L variant tagging isoforms with differing ENaC ubiquitination c...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs10177833	SLC4A5	Intronic variant in the sodium bicarbonate cotransporter gene strongly associ...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs12606138	NEDD4L	Intronic variant in NEDD4L associated with reading ability and dyslexia susce...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs17249754	ATP2B1	Intronic variant in the ATP2B1 calcium pump gene; the common G allele reduces...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs12917707	UMOD	Uromodulin promoter variant — strongest GWAS signal for chronic kidney diseas...	Uric Acid & Kidney Function	Salt Sensitivity	Established
rs1799998	CYP11B2 -344C>T	Promoter variant in aldosterone synthase increasing CYP11B2 transcription, as...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs2004776	AGT	Intronic regulatory variant in angiotensinogen intron I that enhances HNF3β t...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs2270915	NPR3 N521D	Missense variant in NPR3 clearance receptor disrupting Gi protein coupling, i...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs2681472	ATP2B1	Intronic regulatory variant near the PMCA1 calcium pump gene, one of the most...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs35929607	STK39	Intronic variant in the SPAK kinase gene that has been studied for associatio...	Blood Pressure & Hypertension	Salt Sensitivity	Emerging
rs3754777	STK39	Intronic STK39 variant that increases SPAK kinase expression, enhancing phosp...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs3865418	NEDD4L	Intronic NEDD4L variant that tags reduced ubiquitin-ligase activity toward th...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs3910053	NR3C2	Intronic NR3C2 variant associated with salt sensitivity of blood pressure and...	Blood Pressure & Hypertension	Salt Sensitivity	Emerging
rs6997709	KCNK9	Intergenic variant upstream of KCNK9 (TASK3 potassium channel) associated wit...	Arrhythmia & Heart Rhythm	Salt Sensitivity	Moderate
rs4961	ADD1 Gly460Trp	Alpha-adducin missense variant that increases renal tubular sodium reabsorpti...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs5051	AGT G-6A	Promoter variant that increases angiotensinogen gene transcription, raising p...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs5186	AGTR1 A1166C	3' UTR variant in angiotensin II type 1 receptor affecting blood pressure reg...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs549476	NEDD4L	Intronic NEDD4L variant influencing ubiquitin ligase isoform expression and s...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs7305099	WNK1 WNK1 intronic variant	Intronic WNK1 variant where the G allele is associated with increased essenti...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs7571842	SLC4A5	Intronic variant in the renal sodium-bicarbonate cotransporter gene SLC4A5 as...	Blood Pressure & Hypertension	Salt Sensitivity	Strong
rs8094327	NEDD4L	Intronic NEDD4L variant tagging the haplotype block that modulates ENaC sodiu...	Blood Pressure & Hypertension	Salt Sensitivity	Moderate
rs2758151	SGK1	Regulatory tagging SNP near SGK1 (serum/glucocorticoid regulated kinase 1) — ...	Blood Sugar & Diabetes	Salt Sensitivity	Moderate
rs699	AGT M235T	Angiotensinogen level variant affecting blood pressure, sodium sensitivity, a...	Fitness & Body	Salt Sensitivity	Strong