Tag

Skin Cancer

7 genetic variants with this tag.

RSID	Gene	Description	Category
rs16891982	SLC45A2 L374F	Major determinant of light skin pigmentation in Europeans; lighter-skinned in...	Skin & Eyes	Pigmentation Melanoma Risk Sun Sensitivity	Established
rs1800407	OCA2 Arg419Gln	Eye color modifier gene influencing green and hazel eye color through melanos...	Skin & Eyes	Skin & Eyes Eye Color Pigmentation	Strong
rs1805007	MC1R R151C	Strongest "R" allele in the melanocortin-1 receptor, shifting pigment from ph...	Skin & Eyes	Pain Sensitivity Skin Health Anesthesia	Established
rs12350739	BNC2 Regulatory variant	Intergenic enhancer variant controlling BNC2 expression in melanocytes; deter...	Skin & Eyes	Skin Pigmentation Freckling UV Sensitivity	Strong
rs1800975	XPA A23G	5' UTR variant in the XPA DNA damage recognition gene that modulates nucleoti...	Cancer Risk	Cancer Risk DNA Repair Pharmacogenomics	Strong
rs28777	SLC45A2	Intronic pigmentation variant in SLC45A2 strongly associated with skin color,...	Skin & Eyes	Pigmentation Melanoma Risk Sun Sensitivity	Established
rs2228001	XPC Lys939Gln	Missense variant in the DNA damage recognition gene XPC that reduces global-g...	Fitness & Body	DNA Repair Fitness Recovery	Strong