Tag

Smoking Related

5 genetic variants with this tag.

RSID	Gene	Description	Category
rs28929474	SERPINA1 Z allele (E342K)	Most common alpha-1 antitrypsin deficiency variant causing protein misfolding...	Metabolic Enzymes & Rare Disorders	Smoking Related	Established
rs28399433	CYP2A6 *9 (TATA box)	Promoter variant that reduces CYP2A6 expression by ~50%, slowing nicotine met...	Pharmacogenomics	Smoking Related	Strong
rs28399444	CYP2A6 *7 (I471T)	CYP2A6*7 missense variant that nearly abolishes nicotine C-oxidase activity; ...	Pharmacogenomics	Smoking Related	Established
rs4997557	CYP2A6	Rare CYP2A6 missense variant (p.Thr294Ile) that likely reduces nicotine-metab...	Pharmacogenomics	Smoking Related	Emerging
rs8192780	CYP2E1	Downstream regulatory variant near CYP2E1 associated with nasopharyngeal carc...	Pharmacogenomics	Smoking Related	Emerging