Tag

Alcohol

17 genetic variants with this tag.

RSID	Gene	Description	Category
rs1229984	ADH1B His48Arg	ADH1B variant encoding a ~100x faster alcohol dehydrogenase enzyme, causing r...	Mood & Behavior	Alcohol	Established
rs2294918	PNPLA3 PNPLA3 K434E (E434K)	Second PNPLA3 missense variant that reduces hepatic PNPLA3 mRNA and protein e...	Liver Fat	Alcohol	Moderate
rs1420318	FTO	FTO intron 8 variant associated with nominal spine bone mineral density effec...	Fitness & Body	Alcohol	Emerging
rs1693482	ADH1C Arg272Gln (ADH1C1/2)	ADH1C variant defining the fast (ADH1C1, Arg272) vs slow (ADH1C2, Gln272) a...	Mood & Behavior	Alcohol	Strong
rs2066702	ADH1B Arg370Cys	ADH1B*3 variant encoding a superactive alcohol dehydrogenase found almost exc...	Mood & Behavior	Alcohol	Strong
rs6834314	HSD17B13	Intergenic tag SNP in near-perfect linkage disequilibrium with the HSD17B13 s...	Liver Fat	Alcohol	Moderate
rs72613567	HSD17B13 Splice Variant (;A)	Protective adenine insertion disrupting the HSD17B13 splice donor site, produ...	Liver Fat	Alcohol	Established
rs738409	PNPLA3 I148M	Strongest genetic risk factor for non-alcoholic fatty liver disease, progress...	Liver Fat	Alcohol	Established
rs279858	GABRA2 K132K	GABA-A receptor alpha-2 subunit variant affecting alcohol response, anxiety, ...	Mood & Behavior	Alcohol	Strong
rs708272	CETP TaqIB	Influences HDL cholesterol levels and particle size through effects on choles...	Atherogenic Lipoproteins	Alcohol	Strong
rs2031920	CYP2E1 *5B (RsaI)	Promoter variant increasing CYP2E1 inducibility, elevating oxidative stress f...	Pharmacogenomics	Alcohol	Moderate
rs2070672	CYP2E1	CYP2E1 promoter variant affecting enzyme expression and susceptibility to ace...	Pharmacogenomics	Alcohol	Moderate
rs2070676	CYP2E1	Intronic CYP2E1 variant tagging the *1B haplotype; C allele marks reduced CYP...	Pharmacogenomics	Alcohol	Moderate
rs2480256	CYP2E1	3' UTR variant that increases CYP2E1 expression, raising hepatotoxicity risk ...	Pharmacogenomics	Alcohol	Moderate
rs2515641	CYP2E1	Synonymous exon-8 variant that reduces CYP2E1 mRNA and protein expression, al...	Pharmacogenomics	Alcohol	Moderate
rs55897648	CYP2E1 *3 (Val389Ile)	CYP2E1*3 missense variant with no demonstrated change in enzyme activity for ...	Pharmacogenomics	Alcohol	Emerging
rs6413419	CYP2E1 *4 (V179I)	Missense variant (Val179Ile) defining the CYP2E1*4 allele; associated with al...	Pharmacogenomics	Alcohol	Emerging