Tag

Chronic Pain

11 genetic variants with this tag.

RSID	Gene	Description	Category
rs10167914	IL1A IL1A Endometriosis Susceptibility Variant	A regulatory tag SNP in the IL1A/IL1B locus on chromosome 2q13; the G allele ...	Endometriosis & Uterine Health	Chronic Pain	Strong
rs10456100	KCNK5	Intronic variant near KCNK5 that reduces TASK2 potassium channel expression a...	Neurology & Cognition	Chronic Pain	Strong
rs11842874	MCF2L	Intronic variant in MCF2L that acts as a synovial eQTL — A allele carriers ha...	Fitness & Body	Chronic Pain	Strong
rs1800629	TNF -308 G>A	Promoter variant increasing TNF-alpha production approximately 2-fold, associ...	TNF, NF-kB & Inflammatory Cytokines	Chronic Pain	Strong
rs142885915	NPSR1 NPSR1 Endometriosis Risk Variant	An intronic insertion/deletion variant in the neuropeptide S receptor 1 gene ...	Endometriosis & Uterine Health	Chronic Pain	Moderate
rs71575922	SYNE1 SYNE1 Endometriosis Pain Subphenotype Variant	An intronic variant in SYNE1 (Nesprin-1) at the 6q25.1 locus, first identifie...	Endometriosis & Uterine Health	Chronic Pain	Strong
rs2078371	TSPAN2	Regulatory variant in the TSPAN2/NGF locus on chromosome 1p13; the C allele i...	Neurology & Cognition	Chronic Pain	Strong
rs208294	P2RX7 His155Tyr	Gain-of-function missense variant in the P2X7 ATP-gated receptor that increas...	Neurology & Cognition	Chronic Pain	Moderate
rs3791033	KDM4A	Intronic variant in KDM4A histone demethylase associated with problematic opi...	Pharmacogenomics	Chronic Pain	Moderate
rs640561	LRRIQ3	Intergenic variant near LRRIQ3 associated with problematic opioid prescriptio...	Pharmacogenomics	Chronic Pain	Emerging
rs7958311	P2RX7 Arg270His	P2RX7 variant with a unique dual mechanism — gain-of-function in channel open...	Neurology & Cognition	Chronic Pain	Moderate