Tag
Circadian
20 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10462020 | PER3 V647G | Missense variant in circadian clock gene PER3 associated with morning chronot... | Hormones & Sleep | Moderate | |
| rs11071559 | RORA | Intronic variant in the circadian clock regulator RORA; the T allele is prote... | Allergy & Atopic Disease | Moderate | |
| rs1144566 | RGS16 RGS16 H137R | Missense variant in RGS16 that substitutes histidine for arginine at position... | Hormones & Sleep | Moderate | |
| rs11545787 | RASD1 RASD1 photic entrainment variant | 3' UTR variant in RASD1 (Dexras1), a GTPase that gates light signals to the c... | Hormones & Sleep | Strong | |
| rs11605924 | CRY2 Intron Variant | Circadian clock gene variant affecting fasting glucose, hepatic lipid metabol... | Hormones & Sleep | Strong | |
| rs12736689 | RGS16 | Intronic/regulatory variant near RGS16 that is the strongest single-locus mor... | Hormones & Sleep | Strong | |
| rs1369481 | NPAS2 | Intronic variant in the brain-specific circadian transcription factor NPAS2; ... | Hormones & Sleep | Emerging | |
| rs139315125 | PER3 H417R | Rare PER3 missense variant that co-occurs on the FASPS3 haplotype with Pro415... | Hormones & Sleep | Strong | |
| rs1801260 | CLOCK 3111T>C (3'UTR) | Core circadian clock transcription factor variant affecting mRNA stability, a... | Hormones & Sleep | Moderate | |
| rs184039278 | CRY1 CRY1Δ11 | Splice-site variant in the circadian clock gene CRY1 that causes exon 11 skip... | Hormones & Sleep | Strong | |
| rs2066853 | AHR Arg554Lys | Aryl hydrocarbon receptor variant in the transactivation domain that alters A... | Hormones & Sleep | Moderate | |
| rs2675703 | OPN4 | Missense variant (Pro10Leu) in melanopsin, the photopigment driving circadian... | Hormones & Sleep | Emerging | |
| rs34714364 | APH1A APH1A gamma-secretase variant | Synonymous variant in CA14 near APH1A; T allele is associated with morning ch... | Hormones & Sleep | Moderate | |
| rs35333999 | PER2 V903I | Missense variant in core circadian clock gene PER2 that lengthens intrinsic c... | Hormones & Sleep | Strong | |
| rs3923809 | BTBD9 | Second independent intronic BTBD9 variant associated with restless legs syndr... | Hormones & Sleep | Strong | |
| rs4410790 | AHR | Regulatory variant 54 kb upstream of the aryl hydrocarbon receptor gene; the ... | Hormones & Sleep | Strong | |
| rs4446909 | ASMT Promoter A>G | Final enzyme in melatonin synthesis; promoter variant reduces ASMT expression... | Hormones & Sleep | Moderate | |
| rs4753426 | MTNR1B | Promoter variant in the melatonin receptor 1B gene that alters MTNR1B express... | Hormones & Sleep | Moderate | |
| rs516134 | RGS16 RGS16 chronotype variant | Regulatory variant ~20 kb downstream of RGS16 that influences circadian chron... | Hormones & Sleep | Strong | |
| rs55694368 | PER2 PER2 regulatory variant | Upstream regulatory signal near the core circadian clock gene PER2 that shift... | Hormones & Sleep | Strong |