Tag

Cortisol

15 genetic variants with this tag.

RSID	Gene	Description	Category
rs104894085	STAR Q258X (c.772C>T)	Nonsense mutation in STAR that abolishes steroidogenic acute regulatory prote...	Reproductive Hormones	Cortisol	Established
rs10482605	NR3C1	NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle...	Longevity & Aging	Cortisol	Moderate
rs10515522	NR3C1	Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ...	Longevity & Aging	Cortisol	Emerging
rs1360780	FKBP5 Intronic C>T	Co-chaperone of the glucocorticoid receptor that regulates cortisol feedback ...	Mood & Behavior	Cortisol	Strong
rs1743963	SGK1	Intronic SGK1 variant associated with depression susceptibility in coronary h...	Blood Pressure & Hypertension	Cortisol	Emerging
rs137852689	STAR R217T (Arg217Thr)	Pathogenic STAR variant that abolishes steroidogenic acute regulatory protein...	Reproductive Hormones	Cortisol	Established
rs12086634	HSD11B1 Intron 3 variant	Modulates local cortisol activation from cortisone in liver and adipose tissu...	Hormones & Sleep	Cortisol	Moderate
rs258750	NR3C1 NR3C1 Intronic Variant (c.2181+244A>G)	Intronic NR3C1 variant tagging glucocorticoid receptor gene haplotype blocks ...	Reproductive Hormones	Cortisol	Moderate
rs6162	CYP17A1 His46=	Synonymous coding variant in CYP17A1 that tags a haplotype linked to altered ...	Reproductive Hormones	Cortisol	Moderate
rs41423247	NR3C1 BclI	Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s...	Mood & Behavior	Cortisol	Strong
rs80358216	HSD3B2 Trp171X	Pathogenic nonsense variant introducing a premature stop codon at position 17...	Reproductive Hormones	Cortisol	Established
rs2918418	NR3C1	Intronic NR3C1 variant with CC genotype enriched in Polish centenarians; GG g...	Longevity & Aging	Cortisol	Emerging
rs2963154	NR3C1	Intronic NR3C1 variant with TT genotype enriched in Polish centenarians; C al...	Longevity & Aging	Cortisol	Emerging
rs7647305	ETV5	GWAS obesity locus near ETV5 — affects hypothalamic appetite regulation and f...	Appetite & Obesity	Cortisol	Moderate
rs9556979	STK24 HPA Axis Regulation	Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur...	Mood & Behavior	Cortisol	Moderate