Tag
Folate
22 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10380 | MTRR His595Tyr | Missense variant in methionine synthase reductase that impairs B12 reactivati... | Methylation & Detox | Moderate | |
| rs1051266 | SLC19A1 G80A (His27Arg) | Folate transporter — how well folate gets into your cells | Methylation & Detox | Moderate | |
| rs10925239 | MTR | Deep intronic MTR variant associated with reduced cleft lip/palate risk via l... | Methylation & Detox | Emerging | |
| rs10925254 | MTR | Deep intronic MTR variant associated with reduced cleft lip/palate risk via l... | Methylation & Detox | Emerging | |
| rs10925260 | MTR | Intronic MTR variant associated with neural tube defect risk | Methylation & Detox | Emerging | |
| rs11545076 | GGH -124T>G | Promoter variant that increases GGH expression, accelerating hydrolysis of in... | Methylation & Detox | Moderate | |
| rs11627387 | MTHFD1 | Intronic variant in the cytoplasmic trifunctional folate enzyme MTHFD1, assoc... | Methylation & Detox | Moderate | |
| rs3760775 | FUT6 | Near-gene regulatory variant near FUT6 that lowers circulating vitamin B12 | Vitamins & Nutrient Absorption | Moderate | |
| rs1532268 | MTRR MTRR S175L | Missense variant in methionine synthase reductase that raises homocysteine wh... | Methylation & Detox | Moderate | |
| rs1800909 | GGH c.16T>C (p.Cys6Arg) | Signal-peptide missense variant; C allele carriers show modestly lower plasma... | Methylation & Detox | Moderate | |
| rs1801133 | MTHFR C677T | Key enzyme for converting folate to its active methylfolate form | Methylation & Detox | Established | |
| rs6922269 | MTHFD1L | Intronic variant in the mitochondrial folate enzyme MTHFD1L, associated with ... | Coronary Artery Disease & Atherosclerosis | Strong | |
| rs1802059 | MTRR | Synonymous MTRR variant (c.1911G>A) associated with congenital heart disease ... | Methylation & Detox | Emerging | |
| rs61735836 | FTCD | Missense variant in the FTCD enzyme that impairs one-carbon unit transfer fro... | Vitamins & Nutrient Absorption | Strong | |
| rs1979277 | SHMT1 C1420T | Alters one-carbon metabolism and folate distribution; influences cancer risk ... | Methylation & Detox | Moderate | |
| rs202676 | FOLH1 T484A | Reduces intestinal folate hydrolase activity, impairing absorption of dietary... | Methylation & Detox | Moderate | |
| rs2236225 | MTHFD1 G1958A | Folate processing enzyme — reduced stability increases choline need | Methylation & Detox | Strong | |
| rs234706 | CBS C699T | Common synonymous variant in the CBS gene | Methylation & Detox | Moderate | |
| rs3788205 | SLC19A1 SLC19A1 intronic variant | Intronic marker in the folate transporter gene | Methylation & Detox | Emerging | |
| rs61886492 | FOLH1 H475Y | Reduces intestinal GCPII enzyme activity by 53%, paradoxically raising circul... | Methylation & Detox | Strong | |
| rs7946 | PEMT Val175Met | Phosphatidylcholine production — affects dietary choline requirements | Methylation & Detox | Strong | |
| rs828903 | MTHFD2 | Intronic variant in the mitochondrial folate enzyme MTHFD2, influencing one-c... | Methylation & Detox | Moderate |