Tag

Gout

8 genetic variants with this tag.

RSID	Gene	Description	Category
rs35829419	NLRP3 Q705K	Gain-of-function missense variant in the NLRP3 inflammasome sensor that eleva...	Immune & Gut	Immune & Gut Inflammation Gout	Moderate
rs2231142	ABCG2 Q141K	Reduces ABCG2 transporter function affecting rosuvastatin levels and uric aci...	Pharmacogenomics	Drug Metabolism Statins Cardiovascular	Established
rs3733591	SLC2A9 Arg265His	Missense variant in the major renal urate transporter; the Arg265 (C) allele ...	Nutrition & Metabolism	Gout Cardiovascular Diet	Strong
rs4293393	UMOD	UMOD promoter variant affecting uromodulin expression, linked to CKD, salt-se...	Nutrition & Metabolism	Kidney Disease Hypertension Gout	Established
rs505802	SLC22A12	Upstream regulatory variant in the URAT1 urate reabsorption transporter gene;...	Nutrition & Metabolism	Gout Uric Acid Cardiovascular	Established
rs2078267	SLC22A11	Intronic variant in the OAT4 renal urate transporter that modulates uric acid...	Nutrition & Metabolism	Uric Acid Gout Diet	Strong
rs11942223	SLC2A9	Intronic SLC2A9 variant tagging an independent urate-transport signal; the pr...	Nutrition & Metabolism	Gout Uric Acid Cardiovascular	Strong
rs16890979	SLC2A9	Missense variant in the GLUT9 renal urate transporter; the T allele (Val→Ile ...	Nutrition & Metabolism	Gout Uric Acid Diet	Moderate