Tag

Growth Factors

11 genetic variants with this tag.

RSID	Gene	Description	Category
rs1059369	GDF15 S48T	GDF15 signal-peptide missense variant that tags a haplotype influencing circu...	Fat Storage & Energy	Growth Factors	Moderate
rs12946942	SOX9	Intergenic variant in the SOX9 upstream regulatory region on chromosome 17q24...	Innate Immunity & Infection Defense	Growth Factors	Strong
rs2178575	ERBB4 ERBB4/HER4 PCOS Folliculogenesis	An intronic variant in ERBB4 on chromosome 2q34; the A allele tags reduced ER...	Fertility & Ovarian Function	Growth Factors	Strong
rs1800471	TGFB1 R25P (Arg25Pro)	Signal-peptide missense variant altering TGF-β1 secretion levels, associated ...	Vascular Inflammation & Remodeling	Growth Factors	Moderate
rs1805097	IRS2 Gly1057Asp	Missense IRS2 variant where Asp/Asp homozygotes are twice as likely to reach ...	Longevity & Aging	Growth Factors	Moderate
rs35333564	MIR4300HG AIS Progression Locus (intron 1 enhancer indel)	Intronic indel in the MIR4300 host gene that reduces enhancer activity and MI...	Innate Immunity & Infection Defense	Growth Factors	Moderate
rs1805086	MSTN K153R	Affects myostatin's ability to limit muscle growth, influencing muscle mass a...	Fitness & Body	Growth Factors	Moderate
rs200330818	GDF2	Rare missense variant in BMP9/GDF2 that impairs processing of the mature BMP9...	Vascular Inflammation & Remodeling	Growth Factors	Moderate
rs2229765	IGF1R c.3179G>A (E1013E)	Synonymous IGF1R variant associated with lower circulating IGF-1 levels and e...	Longevity & Aging	Growth Factors	Moderate
rs7030781	VEGFA VEGFA Regulatory Co-variant	Chromosome 9 regulatory co-variant near a lncRNA locus that co-segregates wit...	Vascular Inflammation & Remodeling	Growth Factors	Emerging
rs2854747	IGFBP3	Intronic variant in IGFBP3 — the gene encoding the main carrier protein for I...	Fat Storage & Energy	Growth Factors	Moderate