Tag

Histamine

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs10156191	AOC1 Thr16Met	DAO structural variant affecting enzyme activity and histamine degradation	Methylation & Detox	Histamine	Strong
rs1049742	AOC1	Missense variant in the diamine oxidase enzyme that contributes to reduced hi...	Methylation & Detox	Histamine	Moderate
rs1049793	AOC1 His645Asp	DAO structural variant near the catalytic domain affecting histamine degradation	Methylation & Detox	Histamine	Strong
rs1050891	HNMT 3'UTR variant	Histamine breakdown in blood and tissues - uses methyl groups from SAM	Methylation & Detox	Histamine	Moderate
rs11558538	HNMT Thr105Ile	HNMT structural variant - reduces enzyme stability and histamine clearance in...	Methylation & Detox	Histamine	Strong
rs1799983	NOS3 Glu298Asp	Nitric oxide production - reduced activity increases cardiovascular risk and ...	Methylation & Detox	Histamine	Established
rs2052129	AOC1 promoter variant	Histamine breakdown in gut - reduced activity means dietary histamine accumul...	Methylation & Detox	Histamine	Strong
rs2070744	NOS3 T-786C promoter	NOS3 expression - controls how much eNOS enzyme is produced for nitric oxide ...	Methylation & Detox	Histamine	Strong
rs4684059	HRH1	Intronic variant in the histamine H1 receptor gene associated with altered re...	Methylation & Detox	Histamine	Emerging