Tag

Hormones

20 genetic variants with this tag.

RSID	Gene	Description	Category
rs2479106	DENND1A	Intronic variant in the androgen-regulating DENND1A gene associated with poly...	Fertility & Reproductive Health	PCOS Fertility Reproductive Health	Strong
rs11206244	DIO1 C785T	Common variant in the 3' UTR of the DIO1 gene affecting thyroid hormone metab...	Hormones & Sleep	Thyroid Hormones Metabolism	Strong
rs13405728	LHCGR	Intronic variant in the LH/choriogonadotropin receptor gene associated with P...	Fertility & Reproductive Health	PCOS Fertility Reproductive Health	Strong
rs13164856	IRF1	PCOS-susceptibility tag SNP at the IRF1/RAD50 5q31 locus, associated with ele...	Fertility & Reproductive Health	PCOS Fertility Reproductive Health	Strong
rs700518	CYP19A1 Val80	Synonymous variant in aromatase gene affecting estrogen production, bone dens...	Hormones & Sleep	Hormones Estrogen Bone Health	Strong
rs11031006	FSHB	Distal enhancer variant ~26 kb upstream of FSHB associated with FSH levels, d...	Fertility & Reproductive Health	Fertility Hormones Gonadotropins	Strong
rs12700667	7p15.2 (near HOXA10/HOXA11)	Intergenic GWAS locus upstream of homeobox genes HOXA10 and HOXA11 that may i...	Fertility & Reproductive Health	Endometriosis Reproductive Health Fertility	Established
rs2180439	WNT10A	Lead SNP at the 20p11 locus, the strongest autosomal genetic risk factor for ...	Skin & Eyes	Skin, Hair & Pigmentation Aging Hormones	Strong
rs1046089	PRRC2A Arg1740His	Missense variant in PRRC2A (HLA-B associated transcript) linked to age at nat...	Fertility & Reproductive Health	Menopause Ovarian Reserve Reproductive Health	Strong
rs2303369	FNDC4	Intronic variant in FNDC4 (fibronectin type III domain containing 4) on chrom...	Fertility & Reproductive Health	Ovarian Reserve Menopause Fertility	Strong
rs7759938	LIN28B	Regulatory variant near LIN28B associated with puberty timing — the T allele ...	Fertility & Reproductive Health	Puberty Timing Fertility Reproductive Health	Established
rs6165	FSHR Ala307Thr (T307A)	Missense variant in the extracellular domain of the FSH receptor that removes...	Fertility & Reproductive Health	Fertility Reproductive Health IVF	Strong
rs13394619	GREB1	Intronic variant in GREB1, an estrogen-responsive gene; the G allele is assoc...	Fertility & Reproductive Health	Endometriosis Fertility Reproductive Health	Established
rs7521902	WNT4	Intronic variant near WNT4 on chromosome 1p36.12 associated in multiple GWAS ...	Fertility & Reproductive Health	Endometriosis Uterine Fibroids Fertility	Strong
rs314276	LIN28B	Intronic variant in LIN28B associated with puberty timing — the C allele may ...	Fertility & Reproductive Health	Puberty Timing Fertility Reproductive Health	Established
rs5443	GNB3 C825T	Synonymous exon-10 variant that triggers alternative splicing of the G-protei...	Hormones & Sleep	Hypertension Blood Pressure Antidepressants	Strong
rs6166	FSHR Asn680Ser (N680S)	Affects FSH receptor sensitivity, determining ovarian response to FSH stimula...	Hormones & Sleep	Reproductive Health Hormones Fertility	Strong
rs965513	FOXE1	Strongest GWAS thyroid locus — regulatory variant near FOXE1 affecting thyroi...	Hormones & Sleep	Thyroid Hormones & Thyroid Cancer Risk	Strong
rs2293275	LHCGR Asn312Ser (N312S)	Affects LH/hCG receptor sensitivity near a glycosylation site, influencing ov...	Fertility & Reproductive Health	Reproductive Health Hormones Fertility	Strong
rs1137101	LEPR Q223R (Gln223Arg)	Common leptin receptor variant affecting satiety signaling and metabolic health	Nutrition & Metabolism	Nutrition & Metabolism Obesity Diabetes	Moderate