Tag
HPA Axis
10 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10482605 | NR3C1 | NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle... | Longevity & Aging | Moderate | |
| rs10515522 | NR3C1 | Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ... | Longevity & Aging | Emerging | |
| rs12086634 | HSD11B1 Intron 3 variant | Modulates local cortisol activation from cortisone in liver and adipose tissu... | Hormones & Sleep | Moderate | |
| rs1545843 | SLC6A15 SLC6A15 depression risk variant | Variant reducing SLC6A15 expression in hippocampus; AA carriers show increase... | Mood & Behavior | Strong | |
| rs2522833 | PCLO Ser4814Ala | Missense variant in the C2A calcium-binding domain of presynaptic scaffolding... | Mood & Behavior | Moderate | |
| rs7647305 | ETV5 | GWAS obesity locus near ETV5 | Appetite & Obesity | Moderate | |
| rs2963154 | NR3C1 | Intronic NR3C1 variant with TT genotype enriched in Polish centenarians; C al... | Longevity & Aging | Emerging | |
| rs9556979 | STK24 HPA Axis Regulation | Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur... | Mood & Behavior | Moderate | |
| rs6198 | NR3C1 9β | 3'UTR variant that increases glucocorticoid-resistant GRβ isoform expression,... | Longevity & Aging | Strong | |
| rs9470080 | FKBP5 | Intronic FKBP5 variant in the stress-aging haplotype block — T allele carrier... | Longevity & Aging | Strong |