Tag

HPA Axis

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs41423247	NR3C1 BclI	Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s...	Brain & Mental Health	Mental Health Stress Response Cortisol	Strong
rs12086634	HSD11B1 Intron 3 variant	Modulates local cortisol activation from cortisone in liver and adipose tissu...	Hormones & Sleep	Cortisol HPA Axis Metabolic Syndrome	Moderate
rs6198	NR3C1 9β	3'UTR variant that increases glucocorticoid-resistant GRβ isoform expression,...	Longevity & Aging	Longevity Aging HPA Axis	Strong
rs2963154	NR3C1	Intronic NR3C1 variant with TT genotype enriched in Polish centenarians; C al...	Longevity & Aging	Longevity Aging HPA Axis	Emerging
rs10515522	NR3C1	Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ...	Longevity & Aging	Longevity Aging Stress Response	Emerging
rs10482605	NR3C1	NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle...	Longevity & Aging	Longevity Aging HPA Axis	Moderate
rs9470080	FKBP5	Intronic FKBP5 variant in the stress-aging haplotype block — T allele carrier...	Longevity & Aging	Longevity Aging HPA Axis	Strong
rs2918418	NR3C1	Intronic NR3C1 variant with CC genotype enriched in Polish centenarians; GG g...	Longevity & Aging	Longevity Aging HPA Axis	Emerging
rs7647305	ETV5	GWAS obesity locus near ETV5 — affects hypothalamic appetite regulation and f...	Nutrition & Metabolism	Obesity Appetite Dopamine	Moderate