Tag
Iron
12 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1800562 | HFE C282Y | Primary variant causing hereditary hemochromatosis type 1, disrupting iron re... | Iron & Mineral Transport | Established | |
| rs10839553 | CCKBR | Intronic variant near the cholecystokinin B receptor gene associated with res... | Neurology & Cognition | Strong | |
| rs2075674 | TFR2 TFR2 Ala617 variant | Synonymous coding variant in transferrin receptor 2 with potential splice-mod... | Iron & Mineral Transport | Emerging | |
| rs2235321 | TMPRSS6 TMPRSS6 synonymous variant (hepcidin modulator) | Synonymous coding variant in TMPRSS6 associated with hepcidin levels and iron... | Vitamins & Nutrient Absorption | Moderate | |
| rs228921 | TMPRSS6 TMPRSS6 iron regulation variant | Upstream regulatory variant near TMPRSS6 that independently lowers hemoglobin... | Iron & Mineral Transport | Strong | |
| rs2413450 | TMPRSS6 TMPRSS6 iron regulation variant | Intronic TMPRSS6 variant associated with lower MCV, MCH, and hemoglobin level... | Iron & Mineral Transport | Strong | |
| rs5756504 | TMPRSS6 TMPRSS6 variant | Intronic TMPRSS6 variant associated with hemoglobin levels and erythrocyte pa... | Iron & Mineral Transport | Moderate | |
| rs7385804 | TFR2 | Intronic variant in transferrin receptor 2 that tags altered TFR2 expression ... | Iron & Mineral Transport | Strong | |
| rs855791 | TMPRSS6 Ala736Val | Master regulator of iron absorption via hepcidin control — the strongest comm... | Iron & Mineral Transport | Established | |
| rs12693542 | SLC40A1 | Regulatory variant upstream of ferroportin (the sole cellular iron exporter) ... | Neurology & Cognition | Strong | |
| rs4434553 | TFR2 TFR2 upstream variant | Regulatory variant 2 kb upstream of TFR2 that modulates hepcidin production a... | Vitamins & Nutrient Absorption | Emerging | |
| rs3923809 | BTBD9 | Second independent intronic BTBD9 variant associated with restless legs syndr... | Hormones & Sleep | Strong |