Tag
Leptin
9 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1137101 | LEPR Q223R (Gln223Arg) | Common leptin receptor variant in the leptin-binding domain affecting satiety... | Hormones & Sleep | Moderate | |
| rs11152221 | MC4R MC4R Proximal LD Block Variant | Intergenic variant in the proximal 3' regulatory block near MC4R associated w... | Appetite & Obesity | Strong | |
| rs4788102 | SH2B1 SH2B1/APOBR locus variant | Intronic variant at the SH2B1 locus on chromosome 16p11.2 — a key adaptor pro... | Appetite & Obesity | Strong | |
| rs571312 | MC4R MC4R Regulatory Variant (Appetite Signaling) | Regulatory variant upstream of MC4R associated with increased caloric intake,... | Appetite & Obesity | Strong | |
| rs7498665 | SH2B1 Thr484Ala | Obesity GWAS missense variant in SH2B1 that impairs leptin signaling and incr... | Appetite & Obesity | Strong | |
| rs7799039 | LEP G-2548A | Promoter variant that increases leptin gene expression in adipose tissue, ele... | Appetite & Obesity | Moderate | |
| rs3787348 | PTPN1 PTPN1 intronic variant | Intronic PTPN1 tag SNP within the 100-kb insulin-resistance haplotype block; ... | Blood Sugar & Diabetes | Moderate | |
| rs6067484 | PTPN1 PTPN1 rs6067484 | Intronic PTPN1 tag SNP raising LDL cholesterol risk in lean individuals | Blood Sugar & Diabetes | Moderate | |
| rs941798 | PTPN1 | Intronic PTPN1 variant tagging a haplotype block associated with reduced insu... | Blood Sugar & Diabetes | Moderate |