Tag

Mood

11 genetic variants with this tag.

RSID	Gene	Description	Category
rs225014	DIO2 Thr92Ala	Affects conversion of inactive T4 to active T3 thyroid hormone in brain, pitu...	Hormones & Sleep	Hormones & Thyroid Neurotransmitters Metabolism	Strong
rs6323	MAOA R297R	X-linked monoamine oxidase A variant affecting enzyme activity and neurotrans...	Brain & Mental Health	Mental Health Neurotransmitters Mood	Strong
rs25531	SLC6A4 A>G	Promoter SNP near 5-HTTLPR that modifies serotonin transporter expression and...	Brain & Mental Health	Mental Health Neurotransmitters Antidepressants	Moderate
rs2287161	CRY1 3' Downstream G>C	Cryptochrome 1 circadian gene variant influencing glucose metabolism, sleep t...	Hormones & Sleep	Circadian Sleep Chronotype	Strong
rs10462020	PER3 V647G	Missense variant in circadian clock gene PER3 associated with morning chronot...	Hormones & Sleep	Circadian Sleep Chronotype	Moderate
rs1006737	CACNA1C	L-type calcium channel gene variant affecting mood regulation, emotional proc...	Brain & Mental Health	Mental Health Brain Health Mood	Strong
rs2271933	HCRTR1 Ile408Val	Missense variant in the orexin/hypocretin receptor 1 that alters G-protein si...	Brain & Mental Health	Migraine Mood Anxiety	Moderate
rs1800883	HTR5A	Promoter/5' UTR variant in the serotonin 5-HT5A receptor gene affecting recep...	Brain & Mental Health	Serotonin Neurotransmitters Mental Health	Moderate
rs956572	BCL2	Intronic variant in the anti-apoptotic gene BCL2 that affects BCL2 expression...	Brain & Mental Health	Brain Health Mental Health Neuroprotection	Moderate
rs208294	P2RX7 His155Tyr	Gain-of-function missense variant in the P2X7 ATP-gated receptor that increas...	Brain & Mental Health	Neuroinflammation Pain Sensitivity Chronic Pain	Moderate
rs2230912	P2RX7 Gln460Arg	Missense variant in the C-terminal domain of the P2X7 receptor that disrupts ...	Brain & Mental Health	Neuroinflammation Mental Health Mood	Moderate