Tag
Mood
20 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1006737 | CACNA1C | L-type calcium channel gene variant affecting mood regulation, emotional proc... | Mood & Behavior | Strong | |
| rs10462020 | PER3 V647G | Missense variant in circadian clock gene PER3 associated with morning chronot... | Hormones & Sleep | Moderate | |
| rs10514299 | TMEM161B-MEF2C TMEM161B-MEF2C intergenic variant | Intronic variant near the MEF2C transcription factor locus associated with in... | Mood & Behavior | Strong | |
| rs10786831 | SORCS3 SORCS3 Depression Variant | Intronic variant in the neurotrophin sorting receptor SORCS3, the top GWAS hi... | Mood & Behavior | Strong | |
| rs11599236 | SORCS3 SORCS3 Neurotrophin Sorting | Intronic variant in the BDNF-receptor trafficking gene SORCS3, associated wit... | Mood & Behavior | Strong | |
| rs1369481 | NPAS2 | Intronic variant in the brain-specific circadian transcription factor NPAS2; ... | Hormones & Sleep | Emerging | |
| rs139315125 | PER3 H417R | Rare PER3 missense variant that co-occurs on the FASPS3 haplotype with Pro415... | Hormones & Sleep | Strong | |
| rs2271933 | HCRTR1 Ile408Val | Missense variant in the orexin/hypocretin receptor 1 that alters G-protein si... | Mood & Behavior | Moderate | |
| rs2522833 | PCLO Ser4814Ala | Missense variant in the C2A calcium-binding domain of presynaptic scaffolding... | Mood & Behavior | Moderate | |
| rs25531 | SLC6A4 A>G | Promoter SNP near 5-HTTLPR that modifies serotonin transporter expression and... | Mood & Behavior | Moderate | |
| rs225014 | DIO2 Thr92Ala | Affects conversion of inactive T4 to active T3 thyroid hormone in brain, pitu... | Hormones & Sleep | Strong | |
| rs2675703 | OPN4 | Missense variant (Pro10Leu) in melanopsin, the photopigment driving circadian... | Hormones & Sleep | Emerging | |
| rs4702 | FURIN proBDNF Processing Variant | A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si... | Mood & Behavior | Moderate | |
| rs6323 | MAOA R297R | X-linked monoamine oxidase A variant affecting enzyme activity and neurotrans... | Mood & Behavior | Strong | |
| rs4746 | GLO1 Glu111Ala | Missense variant in glyoxalase 1 reducing enzyme activity, allowing methylgly... | Hormones & Sleep | Moderate | |
| rs9556979 | STK24 HPA Axis Regulation | Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur... | Mood & Behavior | Moderate | |
| rs956572 | BCL2 | Intronic variant in the anti-apoptotic gene BCL2 that affects BCL2 expression... | Mood & Behavior | Moderate | |
| rs208294 | P2RX7 His155Tyr | Gain-of-function missense variant in the P2X7 ATP-gated receptor that increas... | Neurology & Cognition | Moderate | |
| rs2230912 | P2RX7 Gln460Arg | Missense variant in the C-terminal domain of the P2X7 receptor that disrupts ... | Neurology & Cognition | Moderate | |
| rs4680 | COMT Val158Met | Dopamine/catecholamine breakdown — affects stress response and methyl donor t... | Methylation & Detox | Established |