Tag

Nitric Oxide

23 genetic variants with this tag.

RSID	Gene	Description	Category
rs1049255	CYBA CYBA 3'UTR A640G	3'UTR variant in the NADPH oxidase p22-phox subunit affecting superoxide gene...	Vascular Inflammation & Remodeling	Nitric Oxide	Moderate
rs10918594	NOS1AP	Regulatory variant upstream of NOS1AP (CAPON) associated with QT interval pro...	Arrhythmia & Heart Rhythm	Nitric Oxide	Strong
rs10483099	QDPR	Intronic variant near QDPR that affects BH4 recycling efficiency, influencing...	Methylation & Detox	Nitric Oxide	Emerging
rs10841496	PDE3A	5' UTR variant in phosphodiesterase 3A that may alter PDE3A expression, affec...	Blood Pressure & Hypertension	Nitric Oxide	Emerging
rs2070699	EDN1 EDN1 G2288T Intronic Variant	Intronic EDN1 variant modulating endothelin-1 expression; the T allele associ...	Blood Pressure & Hypertension	Nitric Oxide	Moderate
rs1154404	ADH5 ADH5 Asthma Risk Haplotype Variant	Intronic variant in ADH5 (GSNOR) in near-complete LD (r²=0.99) with adjacent ...	Allergy & Atopic Disease	Nitric Oxide	Moderate
rs3918226	NOS3	NOS3 promoter variant that reduces eNOS expression and increases hypertension...	Blood Pressure & Hypertension	Nitric Oxide	Strong
rs4236601	CAV1	Intergenic variant near caveolin genes affecting primary open-angle glaucoma ...	Skin & Eyes	Nitric Oxide	Strong
rs12598836	HMOX2	Intronic variant near heme oxygenase 2 (HMOX2) associated with migraine-with-...	Neurology & Cognition	Nitric Oxide	Moderate
rs5068	NPPA	3'UTR variant that disrupts miR-425 binding, increasing atrial natriuretic pe...	Blood Pressure & Hypertension	Nitric Oxide	Strong
rs5335	EDNRA	3' UTR variant in the endothelin receptor type A gene associated with ambulat...	Blood Pressure & Hypertension	Nitric Oxide	Moderate
rs374304304	ASL ASL Arg94Cys	Pathogenic missense variant in argininosuccinate lyase that reduces urea cycl...	Metabolic Enzymes & Rare Disorders	Nitric Oxide	Established
rs841	GCH1	Intronic/3'UTR GCH1 variant tagging reduced tetrahydrobiopterin (BH4) synthes...	Blood Pressure & Hypertension	Nitric Oxide	Moderate
rs1799983	NOS3 Glu298Asp	Nitric oxide production - reduced activity increases cardiovascular risk and ...	Methylation & Detox	Nitric Oxide	Established
rs2779249	NOS2 Promoter -1026C/A	Functional promoter variant that increases iNOS transcriptional activity up t...	Longevity & Aging	Nitric Oxide	Moderate
rs4855559	MYH15	Intronic variant in the myosin heavy chain 15 gene associated with impaired c...	Cardiomyopathy & Structural Heart	Nitric Oxide	Emerging
rs1808593	NOS3	Intronic NOS3 variant associated with ankle-brachial index and peripheral art...	Methylation & Detox	Nitric Oxide	Moderate
rs2070744	NOS3 T-786C promoter	NOS3 expression - controls how much eNOS enzyme is produced for nitric oxide ...	Methylation & Detox	Nitric Oxide	Strong
rs2602899	ADH5 ADH5 Promoter NF-kB Variant	Regulatory SNP in the ADH5 promoter at a potential NF-kB binding site; the pr...	Allergy & Atopic Disease	Nitric Oxide	Moderate
rs2851301	ADH5 ADH5 Second NF-kB Site Variant	Upstream promoter variant in ADH5 at a potential NF-kB binding site; the mino...	Allergy & Atopic Disease	Nitric Oxide	Emerging
rs28730619	ADH5	Intronic variant in ADH5 (GSNOR) associated with elevated childhood asthma ri...	Allergy & Atopic Disease	Nitric Oxide	Moderate
rs891512	NOS3	Intronic NOS3 variant that alters splicing factor binding and is associated w...	Methylation & Detox	Nitric Oxide	Moderate
rs8007267	GCH1	Promoter variant affecting GTP cyclohydrolase 1 expression and pain sensitivi...	Neurology & Cognition	Nitric Oxide	Strong