Tag

Nutrition & Metabolism

17 genetic variants with this tag.

RSID	Gene	Description	Category
rs1137101	LEPR Q223R (Gln223Arg)	Common leptin receptor variant in the leptin-binding domain affecting satiety...	Hormones & Sleep	Nutrition & Metabolism	Moderate
rs2278651	SLC30A1 ZnT1 variant	Intronic variant in SLC30A1 (ZnT1), the primary plasma-membrane zinc efflux t...	Iron & Mineral Transport	Nutrition & Metabolism	Emerging
rs174553	FADS1	Intronic variant in the FADS1 gene cluster that reduces delta-5 desaturase ac...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Strong
rs475688	SLC22A12	Intronic regulatory variant in the URAT1 renal urate transporter gene; the T ...	Uric Acid & Kidney Function	Nutrition & Metabolism	Strong
rs16861205	ADIPOQ	Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is...	Fat Storage & Energy	Nutrition & Metabolism	Moderate
rs17606561	ELOVL2	3'-UTR variant in ELOVL2 associated with altered EPA-to-DHA conversion; A all...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Moderate
rs17300539	ADIPOQ -11391G>A	Promoter variant affecting adiponectin secretion and metabolic syndrome risk	Fat Storage & Energy	Nutrition & Metabolism	Strong
rs3832024	FMO3 FMO3 c.591_592del	A 2-bp frameshift deletion in FMO3 that creates a premature stop codon at pos...	Vitamins & Nutrient Absorption	Nutrition & Metabolism	Established
rs1862513	RETN -420C>G	Promoter variant that increases resistin expression via Sp1/Sp3 transcription...	Fat Storage & Energy	Nutrition & Metabolism	Moderate
rs2236212	ELOVL2	Intronic variant in ELOVL2 that reduces elongase-2 enzyme activity, impairing...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Moderate
rs2727271	FADS2	Intronic variant in FADS2 (delta-6 desaturase) associated with reduced enzyme...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Moderate
rs7359397	SH2B1 SH2B1 C/T	Regulatory CpG-SNP downstream of SH2B1 that reduces gene expression via allel...	Appetite & Obesity	Nutrition & Metabolism	Moderate
rs266729	ADIPOQ -11391G>C	Promoter variant reducing adiponectin transcription, increasing T2D, NAFLD, a...	Fat Storage & Energy	Nutrition & Metabolism	Strong
rs7498665	SH2B1 Thr484Ala	Obesity GWAS missense variant in SH2B1 that impairs leptin signaling and incr...	Appetite & Obesity	Nutrition & Metabolism	Strong
rs3798713	ELOVL2	Intronic variant in ELOVL2 associated with altered plasma phospholipid PUFA l...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Moderate
rs7061710	FMO3	Intronic FMO3 variant associated with reduced hepatic oxidation of garlic-der...	Vitamins & Nutrient Absorption	Nutrition & Metabolism	Moderate
rs953413	ELOVL2	Intronic enhancer variant in ELOVL2 that controls transcription factor bindin...	Triglycerides & Fatty Acids	Nutrition & Metabolism	Strong