Tag
Omega-3
30 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs1058322 | ADIPOR2 | Intronic ADIPOR2 variant whose T allele reduces receptor expression in immune... | Fat Storage & Energy | Moderate | |
| rs10889160 | CYP2J2 | Intronic CYP2J2 tag SNP; the C allele marks a haplotype associated with incre... | Vascular Inflammation & Remodeling | Moderate | |
| rs13702 | LPL | LPL 3'UTR variant disrupting a microRNA-410 binding site; the C allele abolis... | Triglycerides & Fatty Acids | Strong | |
| rs2738058 | DEFA1A3 | Intergenic variant downstream of the DEFA1A3 alpha-defensin locus; T risk all... | Dental & Oral Health | Strong | |
| rs1535 | FADS2 | Intronic FADS2 variant with stronger independent associations than rs174575 f... | Triglycerides & Fatty Acids | Strong | |
| rs16861205 | ADIPOQ | Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is... | Fat Storage & Energy | Moderate | |
| rs174535 | MYRF | Missense variant in the MYRF/FADS gene cluster region on chromosome 11 associ... | Triglycerides & Fatty Acids | Moderate | |
| rs174537 | FADS1 | Regulatory variant in the FADS1 locus that controls delta-5 desaturase expres... | Triglycerides & Fatty Acids | Strong | |
| rs174541 | FADS1 FADS1 C>G (delta-5 desaturase depth) | Intronic regulatory variant in FADS1 that reduces delta-5 desaturase expressi... | Triglycerides & Fatty Acids | Strong | |
| rs174546 | FADS1 | 3'UTR regulatory variant in FADS1 that disrupts a miR-149-5p binding site, re... | Triglycerides & Fatty Acids | Strong | |
| rs174547 | FADS1 | Omega-3 fatty acid conversion efficiency - affects ability to make EPA/DHA fr... | Triglycerides & Fatty Acids | Strong | |
| rs174553 | FADS1 | Intronic variant in the FADS1 gene cluster that reduces delta-5 desaturase ac... | Triglycerides & Fatty Acids | Strong | |
| rs174561 | FADS1 | Intronic variant in the FADS1 gene cluster that tags a haplotype block contro... | Triglycerides & Fatty Acids | Strong | |
| rs2275913 | IL17A -197G>A | Promoter variant in the NFAT binding site that increases IL-17A transcription... | TNF, NF-kB & Inflammatory Cytokines | Strong | |
| rs174568 | FADS2 FADS2 C>T (delta-6 desaturase) | Intronic regulatory variant in FADS2 encoding delta-6 desaturase, the rate-li... | Triglycerides & Fatty Acids | Moderate | |
| rs35829419 | NLRP3 Q705K | Gain-of-function missense variant in the NLRP3 inflammasome sensor that eleva... | Innate Immunity & Infection Defense | Moderate | |
| rs174572 | FADS2 | Intronic variant in FADS2 that reduces delta-6 desaturase activity, impairing... | Triglycerides & Fatty Acids | Strong | |
| rs4783961 | CETP | CETP promoter variant that raises HDL cholesterol by reducing cholesteryl est... | Cholesterol & Lipoproteins | Moderate | |
| rs662799 | APOA5 -1131T>C | Promoter variant that reduces APOA5 expression, impairing lipoprotein lipase ... | Atherogenic Lipoproteins | Strong | |
| rs174616 | FADS2 FADS2 Haplotype Block Variant | Intronic FADS2 variant; A allele carriers have reduced delta-6 desaturase act... | Triglycerides & Fatty Acids | Strong | |
| rs2072114 | FADS2 FADS2 Intron 1 Variant | Intronic FADS2 haplotype tag SNP — the G allele is linked to altered delta-6 ... | Triglycerides & Fatty Acids | Moderate | |
| rs822391 | ADIPOQ IVS1+407C>T | Intronic variant in the adiponectin gene associated with ischemic stroke risk... | Fat Storage & Energy | Moderate | |
| rs2727270 | FADS2 | Intronic regulatory variant in FADS2; T allele carriers have lower D5D and D6... | Triglycerides & Fatty Acids | Moderate | |
| rs2280275 | CYP2J2 | Intronic variant in CYP2J2 | Pharmacogenomics | Moderate | |
| rs3734398 | ELOVL2 | 3' UTR variant in the ELOVL2 elongase gene that reduces DHA synthesis from it... | Triglycerides & Fatty Acids | Strong | |
| rs4148102 | ABCG1 ABCG1 intronic PUFA-interaction variant | Intronic variant in the ABCG1 cholesterol efflux transporter gene that modifi... | Triglycerides & Fatty Acids | Emerging | |
| rs953413 | ELOVL2 | Intronic enhancer variant in ELOVL2 that controls transcription factor bindin... | Triglycerides & Fatty Acids | Strong | |
| rs968567 | FADS2 FADS2 Promoter D6D Activity Variant | Promoter variant in FADS2 that increases delta-6 desaturase (D6D) expression ... | Triglycerides & Fatty Acids | Moderate | |
| rs99780 | FADS2 | Intronic variant in the FADS1-FADS2 cluster influencing delta-6 desaturase ac... | Triglycerides & Fatty Acids | Moderate | |
| rs4851266 | AFF3 | Intronic variant in the super elongation complex gene AFF3; the T allele incr... | Neurology & Cognition | Strong |