Tag

Omega-3

46 genetic variants with this tag.

RSID	Gene	Description	Category
rs1058322	ADIPOR2	Intronic ADIPOR2 variant whose T allele reduces receptor expression in immune...	Fat Storage & Energy	Omega-3	Moderate
rs10739076	PLGRKT PLGRKT Plasminogen Receptor/Fibrinolysis	Intergenic PCOS susceptibility locus downstream of PLGRKT (plasminogen recept...	Fertility & Ovarian Function	Omega-3	Moderate
rs10848554	ADIPOR2	Intronic ADIPOR2 variant co-associated with cardiovascular disease risk in in...	Fat Storage & Energy	Omega-3	Moderate
rs10889160	CYP2J2	Intronic CYP2J2 tag SNP; the C allele marks a haplotype associated with reduc...	Vascular Inflammation & Remodeling	Omega-3	Moderate
rs13702	LPL	LPL 3'UTR variant disrupting a microRNA-410 binding site; the C allele abolis...	Triglycerides & Fatty Acids	Omega-3	Strong
rs11572325	CYP2J2	Intronic CYP2J2 variant associated with increased myocardial infarction risk ...	Vascular Inflammation & Remodeling	Omega-3	Moderate
rs1535	FADS2	Intronic FADS2 variant with stronger independent associations than rs174575 f...	Triglycerides & Fatty Acids	Omega-3	Strong
rs2738058	DEFA1A3	Intergenic variant downstream of the DEFA1A3 alpha-defensin locus; T risk all...	Dental & Oral Health	Omega-3	Strong
rs17301739	LIPC	Intronic LIPC variant associated with circulating DHA and omega-3 fatty acid ...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174535	MYRF	Missense variant in the MYRF/FADS gene cluster region on chromosome 11 associ...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs174537	FADS1	Regulatory variant in the FADS1 locus that controls delta-5 desaturase expres...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174541	FADS1 FADS1 C>G (delta-5 desaturase depth)	Intronic regulatory variant in FADS1 that reduces delta-5 desaturase expressi...	Triglycerides & Fatty Acids	Omega-3	Strong
rs17222814	ALOX5AP SG13S114 (HapB tag)	Intronic ALOX5AP variant tagging the HapB risk haplotype; the A allele marks ...	Vascular Inflammation & Remodeling	Omega-3	Moderate
rs174546	FADS1	3'UTR regulatory variant in FADS1 that disrupts a miR-149-5p binding site, re...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174547	FADS1	Omega-3 fatty acid conversion efficiency - affects ability to make EPA/DHA fr...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174548	FADS1	Intronic regulatory variant in FADS1 that reduces delta-5 desaturase expressi...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174553	FADS1	Intronic variant in the FADS1 gene cluster that reduces delta-5 desaturase ac...	Triglycerides & Fatty Acids	Omega-3	Strong
rs2275913	IL17A -197G>A	Promoter variant in the NFAT binding site that increases IL-17A transcription...	TNF, NF-kB & Inflammatory Cytokines	Omega-3	Strong
rs174561	FADS1	Intronic variant in the FADS1 gene cluster that tags a haplotype block contro...	Triglycerides & Fatty Acids	Omega-3	Strong
rs174568	FADS2 FADS2 C>T (delta-6 desaturase)	Intronic regulatory variant in FADS2 encoding delta-6 desaturase, the rate-li...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs174572	FADS2	Intronic variant in FADS2 that reduces delta-6 desaturase activity, impairing...	Triglycerides & Fatty Acids	Omega-3	Strong
rs1800206	PPARA Leu162Val (L162V)	Missense variant in PPARA that reduces receptor transcriptional activity, ele...	Fitness & Body	Omega-3	Moderate
rs35829419	NLRP3 Q705K	Gain-of-function missense variant in the NLRP3 inflammasome sensor that eleva...	Innate Immunity & Infection Defense	Omega-3	Moderate
rs174575	FADS2	Intronic variant in FADS2 that reduces delta-6 desaturase activity, impairing...	Triglycerides & Fatty Acids	Omega-3	Strong
rs16861205	ADIPOQ	Intronic ADIPOQ variant in LD with the promoter region; the minor A allele is...	Fat Storage & Energy	Omega-3	Moderate
rs174616	FADS2 FADS2 Haplotype Block Variant	Intronic FADS2 variant tagging the FADS1/FADS2 haplotype block; A allele carr...	Triglycerides & Fatty Acids	Omega-3	Strong
rs662799	APOA5 -1131T>C	Promoter variant that reduces APOA5 expression, impairing lipoprotein lipase ...	Atherogenic Lipoproteins	Omega-3	Strong
rs17606561	ELOVL2	3'-UTR variant in ELOVL2 associated with altered EPA-to-DHA conversion; A all...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs2072114	FADS2 FADS2 Intron 1 Variant	Intronic FADS2 haplotype tag SNP — the G allele is linked to altered delta-6 ...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs1862513	RETN -420C>G	Promoter variant that increases resistin expression via Sp1/Sp3 transcription...	Fat Storage & Energy	Omega-3	Moderate
rs2236212	ELOVL2	Intronic variant in ELOVL2 that reduces elongase-2 enzyme activity, impairing...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs2524299	FADS2	Intronic regulatory variant in FADS2 (Block 2 haplotype) that reduces basal F...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs2727270	FADS2	Intronic regulatory variant in FADS2 that tags a 10-SNP haplotype reducing ba...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs4783961	CETP	CETP promoter variant that raises HDL cholesterol by reducing cholesteryl est...	Cholesterol & Lipoproteins	Omega-3	Moderate
rs2727271	FADS2	Intronic variant in FADS2 (delta-6 desaturase) associated with reduced enzyme...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs2280275	CYP2J2	Intronic variant in CYP2J2 that tags reduced epoxyeicosatrienoic acid (EET) p...	Pharmacogenomics	Omega-3	Moderate
rs3734398	ELOVL2	3' UTR variant in the ELOVL2 elongase gene that reduces DHA synthesis from it...	Triglycerides & Fatty Acids	Omega-3	Strong
rs3798713	ELOVL2	Intronic variant in ELOVL2 associated with altered plasma phospholipid PUFA l...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs3834458	FADS2	A 3-bp deletion in intron 3 of FADS2 that reduces delta-6 desaturase activity...	Triglycerides & Fatty Acids	Omega-3	Strong
rs4148102	ABCG1 ABCG1 intronic PUFA-interaction variant	Intronic variant in the ABCG1 cholesterol efflux transporter gene that modifi...	Triglycerides & Fatty Acids	Omega-3	Emerging
rs6507931	LIPG	Intronic LIPG variant that modulates HDL cholesterol levels, with strongest e...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs822391	ADIPOQ IVS1+407C>T	Intronic variant in the adiponectin gene associated with circulating adiponec...	Fat Storage & Energy	Omega-3	Moderate
rs953413	ELOVL2	Intronic enhancer variant in ELOVL2 that controls transcription factor bindin...	Triglycerides & Fatty Acids	Omega-3	Strong
rs968567	FADS2 FADS2 Promoter D6D Activity Variant	Promoter variant in FADS2 that increases delta-6 desaturase (D6D) expression ...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs99780	FADS2	Intronic variant in the FADS1-FADS2 cluster influencing delta-6 desaturase ac...	Triglycerides & Fatty Acids	Omega-3	Moderate
rs4851266	AFF3	Intronic variant in the super elongation complex gene AFF3; the T allele incr...	Neurology & Cognition	Omega-3	Strong