Tag

Serotonin

15 genetic variants with this tag.

RSID	Gene	Description	Category
rs104893665	SPR Arg150Gly	Pathogenic missense variant in sepiapterin reductase that abolishes BH4 biosy...	Vitamins & Nutrient Absorption	Serotonin	Established
rs10514299	TMEM161B-MEF2C TMEM161B-MEF2C intergenic variant	Intronic variant near the MEF2C transcription factor locus associated with in...	Mood & Behavior	Serotonin	Strong
rs121917746	SPR Q119X	Nonsense variant in sepiapterin reductase that abolishes BH4 biosynthesis, ca...	Vitamins & Nutrient Absorption	Serotonin	Established
rs121917747	SPR	Nonsense variant in sepiapterin reductase creating a premature stop codon (p....	Vitamins & Nutrient Absorption	Serotonin	Established
rs1800883	HTR5A	Promoter/5' UTR variant in the serotonin 5-HT5A receptor gene affecting recep...	Mood & Behavior	Serotonin	Moderate
rs17679445	PNPO Arg116Gln	Missense variant in pyridoxamine 5'-phosphate oxidase that reduces the enzyme...	Hormones & Sleep	Serotonin	Moderate
rs2050122	HTR6	Regulatory variant near the HTR6 serotonin 6 receptor gene associated with ch...	Hormones & Sleep	Serotonin	Moderate
rs4570625	TPH2 G-703T	Promoter variant affecting brain serotonin synthesis enzyme; influences emoti...	Mood & Behavior	Serotonin	Moderate
rs4702	FURIN proBDNF Processing Variant	A 3'UTR regulatory variant where the G allele creates a miR-338-3p binding si...	Mood & Behavior	Serotonin	Moderate
rs6295	HTR1A C-1019G	Functional promoter variant in the serotonin 1A receptor gene that increases ...	Mood & Behavior	Serotonin	Strong
rs2325751	PNPO	Regulatory variant 2 kb upstream of PNPO that may alter expression of the vit...	Hormones & Sleep	Serotonin	Emerging
rs72704544	GPM6A GPM6A Neuronal Membrane Glycoprotein	Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do...	Mood & Behavior	Serotonin	Moderate
rs3816183	HAAO Ile37Val	Missense variant in the kynurenine pathway enzyme HAAO that shifts tryptophan...	Hormones & Sleep	Serotonin	Moderate
rs387907200	SPR	Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe...	Methylation & Detox	Serotonin	Strong
rs6795209	HTR1F	Intergenic variant at the HTR1F locus on chromosome 3; the minor A allele inc...	Neurology & Cognition	Serotonin	Strong