Tag
Appetite
22 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs10150332 | NRXN3 | Obesity and waist circumference GWAS hit in NRXN3 — links reward-circuit syna... | Appetite & Obesity | Strong | |
| rs10515237 | PCSK1 PCSK1 A/G (rs10515237) | Intronic variant in PCSK1 that tags the Q665E-S690T functional haplotype | Appetite & Obesity | Moderate | |
| rs10766383 | NUCB2 | Intronic NUCB2 variant associated with type 2 diabetes risk in females and or... | Hormones & Sleep | Moderate | |
| rs1137101 | LEPR Q223R (Gln223Arg) | Common leptin receptor variant in the leptin-binding domain affecting satiety... | Hormones & Sleep | Moderate | |
| rs11152221 | MC4R MC4R Proximal LD Block Variant | Intergenic variant in the proximal 3' regulatory block near MC4R associated w... | Appetite & Obesity | Strong | |
| rs12970134 | MC4R MC4R region variant | Near-gene variant ~188kb downstream of MC4R associated with increased waist c... | Appetite & Obesity | Strong | |
| rs17782313 | MC4R Near-gene C>T | Intergenic variant 188kb downstream of MC4R affecting appetite regulation, me... | Appetite & Obesity | Strong | |
| rs1943226 | MC4R MC4R third tagSNP | Upstream regulatory tag variant ~3 kb proximal to MC4R, included in MC4R hapl... | Appetite & Obesity | Emerging | |
| rs2229616 | MC4R V103I | Missense variant in MC4R converting valine to isoleucine at position 103; the... | Appetite & Obesity | Strong | |
| rs16147 | NPY C-399T | Promoter variant in neuropeptide Y that modulates NPY expression under stress... | Mood & Behavior | Moderate | |
| rs2815752 | NEGR1 | Top obesity GWAS variant near NEGR1 | Appetite & Obesity | Strong | |
| rs2867125 | TMEM18 TMEM18 regulatory variant (2p25.3) | Regulatory variant at the TMEM18 locus on chromosome 2p25.3 — one of the most... | Appetite & Obesity | Strong | |
| rs29941 | KCTD15 | GWAS obesity locus near KCTD15 | Appetite & Obesity | Moderate | |
| rs476828 | MC4R MC4R-region BMI variant | Intergenic variant in the MC4R regulatory haplotype block, tagging the same a... | Appetite & Obesity | Strong | |
| rs4788102 | SH2B1 SH2B1/APOBR locus variant | Intronic variant at the SH2B1 locus on chromosome 16p11.2 — a key adaptor pro... | Appetite & Obesity | Strong | |
| rs489693 | MC4R MC4R AIWG variant | Intergenic variant near MC4R with genome-wide significant association with an... | Appetite & Obesity | Strong | |
| rs571312 | MC4R MC4R Regulatory Variant (Appetite Signaling) | Regulatory variant upstream of MC4R associated with increased caloric intake,... | Appetite & Obesity | Strong | |
| rs6232 | PCSK1 PCSK1 N221D (Asn221Asp) | Missense variant in PCSK1 encoding an Asn221Asp substitution near the Ca-1 ca... | Appetite & Obesity | Strong | |
| rs6548238 | TMEM18 | Second strongest obesity GWAS locus after FTO | Appetite & Obesity | Strong | |
| rs696217 | GHRL Leu72Met | Missense variant in the ghrelin prepropeptide that impairs postprandial ghrel... | Appetite & Obesity | Moderate | |
| rs7647305 | ETV5 | GWAS obesity locus near ETV5 | Appetite & Obesity | Moderate | |
| rs8087522 | MC4R MC4R A/G (rs8087522) | Upstream regulatory variant near MC4R that may create a transcription factor ... | Appetite & Obesity | Emerging |