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rs6265
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BDNF
Val66Met
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Key neurotrophin variant that controls activity-dependent BDNF release, affec...
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Brain & Mental Health
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Strong
|
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rs1042713
|
ADRB2
Arg16Gly
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Beta-2 adrenergic receptor variant affecting receptor downregulation, exercis...
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Fitness & Body
|
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Strong
|
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rs4253778
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PPARA
intron 7 G/C
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Regulates fatty acid oxidation and muscle fiber composition, influencing endu...
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Fitness & Body
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Moderate
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rs17602729
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AMPD1
C34T (Q12X)
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Enzyme critical for energy production during high-intensity exercise; deficie...
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Fitness & Body
|
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Strong
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rs356182
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SNCA
|
Parkinson's disease GWAS risk variant affecting alpha-synuclein expression an...
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Brain & Mental Health
|
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Strong
|
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rs3736228
|
LRP5
A1330V
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Wnt signaling co-receptor variant affecting bone mineral density and fracture...
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Fitness & Body
|
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Strong
|
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rs9939609
|
FTO
Intron 1 T>A
|
The most strongly replicated obesity-associated variant, affecting body weigh...
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Nutrition & Metabolism
|
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Established
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rs1801253
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ADRB1
Arg389Gly
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Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit...
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Fitness & Body
|
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Strong
|
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rs2016520
|
PPARD
+294T>C
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Regulatory variant that increases PPARD transcription, enhancing fat oxidatio...
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Fitness & Body
|
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Moderate
|
|
rs1053049
|
PPARD
3'UTR variant
|
3'UTR variant in PPARD that acts as the third tag in the elite athlete haplot...
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Fitness & Body
|
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Moderate
|
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rs2267668
|
PPARD
Intron variant (5' region)
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Intronic PPARD variant that impairs aerobic fitness gains and body compositio...
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Fitness & Body
|
|
Moderate
|
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rs891512
|
NOS3
|
Intronic NOS3 variant that alters splicing factor binding and is associated w...
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Nutrition & Metabolism
|
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Moderate
|